Targeting AKT and DNA-PK as a therapeutic strategy in platinum-resistant high-grade serous ovarian cancer

被引：0
|
作者：
Rinne, N. [1 ]
Curry, E. [1 ]
Fotopoulou, C. [1 ]
Gabra, H. [1 ,2 ]
Cunnea, P. [1 ]
机构：
[1] Imperial Coll London, Ovarian Canc Act Res Ctr, Dept Canc & Surg, London, England
[2] AstraZeneca, IMED Biotech Unit, Early Clin Dev, Cambridge, England
来源：
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY | 2019年 / 126卷
关键词：
D O I：
暂无
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
1985
引用
收藏
页码：88 / 89
页数：2
相关论文
共 50 条
  • [41] Prognostic and Therapeutic Relevance of Molecular Subtypes in High-Grade Serous Ovarian Cancer
    Konecny, Gottfried E.
    Wang, Chen
    Hamidi, Habib
    Winterhoff, Boris
    Kalli, Kimberly R.
    Dering, Judy
    Ginther, Charles
    Chen, Hsiao-Wang
    Dowdy, Sean
    Cliby, William
    Gostout, Bobbie
    Podratz, Karl C.
    Keeney, Gary
    Wang, He-Jing
    Hartmann, Lynn C.
    Slamon, Dennis J.
    Goode, Ellen L.
    JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2014, 106 (10):
  • [42] Decreased Levels of GSH Are Associated with Platinum Resistance in High-Grade Serous Ovarian Cancer
    Criscuolo, Daniela
    Avolio, Rosario
    Parri, Matteo
    Romano, Simona
    Chiarugi, Paola
    Matassa, Danilo Swann
    Esposito, Franca
    ANTIOXIDANTS, 2022, 11 (08)
  • [43] High-grade serous Ovarian Cancer: TP53 Mutations and Platinum Response
    Lorenz, Judith
    GEBURTSHILFE UND FRAUENHEILKUNDE, 2024, 84 (07)
  • [44] Kallistatin inhibits tumour progression and platinum resistance in high-grade serous ovarian cancer
    Wu, Huan
    Li, Rongrong
    Zhang, Zhiwei
    Jiang, Huiyang
    Ma, Hanlin
    Yuan, Cunzhong
    Sun, Chenggong
    Li, Yingwei
    Kong, Beihua
    JOURNAL OF OVARIAN RESEARCH, 2019, 12 (01)
  • [45] Platinum Resistance in High-Grade Serous Ovarian Cancer: an Intratumoral Collagen Fiber Implication
    Pavanello, Marina
    Natal, Rodrigo de Andrade
    Ramalho, Susana
    Vassallo, Jose
    de Angelo Andrade, Liliana Aparecida
    Derchain, Sophie
    Sarian, Luis Otavio
    FASEB JOURNAL, 2016, 30
  • [46] The genomic profile of high-grade serous ovarian cancer and its association with platinum resistance
    Montemorano, Lauren
    Lang, Jessica
    Shultz, Zoey
    Farooque, Alma
    Hyun, Meredith
    Chappell, Richard
    Hartenbach, Ellen
    GYNECOLOGIC ONCOLOGY, 2023, 176 : S290 - S291
  • [47] Characterisation of Proteomic heterogeneity following platinum therapy in High-grade Serous Ovarian Cancer
    Wulandari, Ratri
    Nixon, Katherine
    Rama, Nona
    Curry, Ed
    Cunnea, Paula
    Fotopoulou, Christina
    BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2022, 129 : 40 - 41
  • [48] Histopathology and proteomics are synergistic for high-grade serous ovarian cancer platinum response prediction
    Kilim, Oz
    Olar, Alex
    Biricz, Andras
    Madaras, Lilla
    Pollner, Peter
    Szallasi, Zoltan
    Sztupinszki, Zsofia
    Csabai, Istvan
    NPJ PRECISION ONCOLOGY, 2025, 9 (01)
  • [49] Investigating NKAPL, a potential marker for platinum resistance, in high-grade serous ovarian cancer
    Schafer, Lea
    Silva, Romina
    Stewart, Gavin
    O'Toole, Sharon
    Perry, Antoinette
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2024, 34 (SUPPL_3) : A92 - A93
  • [50] Kallistatin inhibits tumour progression and platinum resistance in high-grade serous ovarian cancer
    Huan Wu
    Rongrong Li
    Zhiwei Zhang
    Huiyang Jiang
    Hanlin Ma
    Cunzhong Yuan
    Chenggong Sun
    Yingwei Li
    Beihua Kong
    Journal of Ovarian Research, 12
12345