Long-Term Results (≤ 18 Years) of the Edge-to-Edge Mitral Valve Repair Without Annuloplasty in Degenerative Mitral Regurgitation Implications for the Percutaneous Approach

被引:76
作者
De Bonis, Michele [1 ]
Lapenna, Elisabetta [1 ]
Maisano, Francesco [2 ]
Barili, Fabio [3 ]
La Canna, Giovanni [1 ]
Buzzatti, Nicola [1 ]
Pappalardo, Federico [1 ]
Calabrese, Mariachiara [1 ]
Nisi, Teodora [1 ]
Alfieri, Ottavio [1 ]
机构
[1] IRCCS San Raffaele Sci Inst, Dept Cardiac Surg, I-20132 Milan, Italy
[2] Univ Zurich Hosp, Dept Cardiac Surg, CH-8091 Zurich, Switzerland
[3] S Croce Hosp, Dept Cardiac Surg, Cuneo, Italy
关键词
mitral valve insufficiency; EXTENSIVE CALCIFICATION; DISEASE; ANNULUS; SURGERY; ANULUS;
D O I
10.1161/CIRCULATIONAHA.113.007885
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background-To assess the long-term results of the edge-to-edge mitral repair performed without annuloplasty in degenerative mitral regurgitation (MR). Methods and Results-From 1993 to 2002, 61 patients with degenerative MR were treated with an isolated edge-to-edge suture without any annuloplasty. Annuloplasty was omitted in 36 patients because of heavy annular calcification and in 25 for limited annular dilatation. A double-orifice repair was performed in 53 patients and a commissural edge-to-edge in 8. Hospital mortality was 1.6%. Follow-up was 100% complete (mean length, 9.2+/-4.21 years; median, 9.7; longest, 18.1). Survival at 12 years was 51.3+/-7.75%. At the last echocardiographic examination, MR >= 3+ was demonstrated in 33 patients (55%). At 12 years, freedom from reoperation was 57.8+/-7.21% and freedom from recurrence of MR >= 3+ was 43+/-7.6%. Residual MR > 1+ at hospital discharge was identified as a risk factor for recurrence of MR >= 3+ (hazard ratio, 3.8; 95% confidence interval, 1.7-8.2; P=0.001). In patients with residual MR <= 1+ immediately after surgery, freedom from MR >= 3+ at 5 and 10 years was 80+/-6% and 64+/-7.58%, respectively. Conclusions-In degenerative MR, the overall long-term results of the surgical edge-to-edge technique without annuloplasty are not satisfactory. Early optimal competence (residual MR <= 1+) was associated with higher freedom from recurrent severe regurgitation.
引用
收藏
页码:S19 / S24
页数:6
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