Geographic, ethnic, age-related and temporal variation in the incidence of end-stage renal disease in Europe, Canada and the Asia-Pacific region, 1998-2002

被引：48

作者：

Stewart, J. H. ^{[1
]}

McCredie, M. R. E. ^{[1
]}

Williams, S. M. ^{[1
]}

Fenton, S. S. ^{[1
]}

Trpeski, L. ^{[1
]}

McDonald, S. P. ^{[1
]}

Jager, K. J. ^{[1
]}

van Dijk, P. C. W. ^{[1
]}

Finne, P. ^{[1
]}

Schon, S. ^{[1
]}

Leivestad, T. ^{[1
]}

Lokkegaard, H. ^{[1
]}

Billiouw, J. -M. ^{[1
]}

Kramar, R. ^{[1
]}

Magaz, A. ^{[1
]}

Cleries, M. ^{[1
]}

Garcia-Blasco, M. J. ^{[1
]}

Ioannidis, G. A. ^{[1
]}

Lim, Y. N. ^{[1
]}

Zahid, I. ^{[1
]}

机构：

[1] Univ Otago, Dept Prevent & Social Med, Dunedin, New Zealand

来源：

NEPHROLOGY DIALYSIS TRANSPLANTATION | 2006年 / 21卷 / 08期

关键词：

Asia-Pacific; Canada; end-stage renal disease; Europe; incidence; trends;

D O I：

10.1093/ndt/gfl145

中图分类号：

R3 [基础医学]; R4 [临床医学];

学科分类号：

1001 ; 1002 ; 100602 ;

摘要：

Background. Only unbiased estimates of end-stage renal disease (ESRD) incidence and trends are useful for disease control-identification of risk factors and measuring the effect of intervention. Methods. Age- and sex-standardized incidences (with trends) were calculated for all-cause and diabetic/non-diabetic ESRD for persons aged 0-14, 15-29, 30-44 and 45-64 years in 13 populations identified geographically, and six populations identified by ethnicity. Results. The incidence of ESRD varied most with age, ethnicity and prevalence of diabetes. All non-Europid populations had excess ESRD, chiefly due to rates of type 2 diabetic ESRD that were greater than accounted for by community prevalences of diabetes. Their rates of non-diabetic ESRD also were raised, with contributions from most common primary renal diseases except type 1 diabetic nephropathy and polycystic kidney disease. The ESRD rates generally were low, and more similar than different, in Europid populations, except for variable contributions from type 1 (high in Finland, Sweden, Denmark and Canada) and type 2 (high in Austria and Canada) diabetes. In Europid populations during 1998-2002, all-cause ESRD declined by 2% per year in persons aged 0-44 years, and all non-diabetic ESRD by a similar amount in persons aged 45-64 years, in whom diabetic ESRD had increased by 3% per year. Conclusions. Increased susceptibility to type 2 diabetes and to kidney disease progression characterizes excess ESRD in non-Europid peoples. The decline in all-cause ESRD in young persons, and non-diabetic ESRD in the middle-aged, probably reflects improving management of progressive renal disease.

引用

页码：2178 / 2183

页数：6

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