Preparation and characterization of antithrombogenic chitosan/alginate films with enhanced physical stability by cross-linking using layer-by-layer method

被引：1

作者：

Kyung, Kyu-Hong ^{[1
]}

Kim, Sae-Hoon ^{[2
]}

Shiratori, Seimei ^{[1
]}

机构：

[1] Keio Univ, Sch Integrated Design Engn, Yokohama, Kanagawa 2238522, Japan

[2] Kangnung wonju Natl Univ, Dept Ceram Engn, Kangwon do 210702, South Korea

来源：

ICOMF14 - 14TH INTERNATIONAL CONFERENCE ON ORGANIZED MOLECULAR FILMS (LB 14) | 2013年 / 4卷

基金：

新加坡国家研究基金会;

关键词：

CHITOSAN;

D O I：

10.1051/matecconf/20130405008

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

We successfully fabricated (chitosan/alginate) (CHI/ALG) multilayer thin film by layer-by-layer (LBL) method. Film durability was enhanced by forming cross-linking using heat treatment, glutaraldehyde, and calcium chloride. Indeed, the adsorption of fibrinogen onto CHI/ALG multilayer thin film was determined by QCM system and it was found that physical stability and protein resistance of CHI/ALG films were improved by cross-linking of the films.

引用

页数：4