Preparation and characterization of antithrombogenic chitosan/alginate films with enhanced physical stability by cross-linking using layer-by-layer method

被引：1
|
作者：
Kyung, Kyu-Hong [1 ]
Kim, Sae-Hoon [2 ]
Shiratori, Seimei [1 ]
机构：
[1] Keio Univ, Sch Integrated Design Engn, Yokohama, Kanagawa 2238522, Japan
[2] Kangnung wonju Natl Univ, Dept Ceram Engn, Kangwon do 210702, South Korea
来源：
ICOMF14 - 14TH INTERNATIONAL CONFERENCE ON ORGANIZED MOLECULAR FILMS (LB 14) | 2013年 / 4卷
基金：
新加坡国家研究基金会;
关键词：
CHITOSAN;
D O I：
10.1051/matecconf/20130405008
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
We successfully fabricated (chitosan/alginate) (CHI/ALG) multilayer thin film by layer-by-layer (LBL) method. Film durability was enhanced by forming cross-linking using heat treatment, glutaraldehyde, and calcium chloride. Indeed, the adsorption of fibrinogen onto CHI/ALG multilayer thin film was determined by QCM system and it was found that physical stability and protein resistance of CHI/ALG films were improved by cross-linking of the films.
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页数：4
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