Sequential combination of decitabine and idarubicin synergistically enhances anti-leukemia effect followed by demethylating Wnt pathway inhibitor promoters and downregulating Wnt pathway nuclear target

被引：2

作者：

Li, Kongfei ^{[1
,2
,3
]}

Hu, Chao ^{[1
,3
]}

Mei, Chen ^{[6
]}

Ren, Zhigang ^{[4
]}

Vera, Juan Carlos ^{[5
]}

Zhuang, Zhengping ^{[5
]}

Jin, Jie ^{[1
,3
]}

Tong, Hongyan ^{[1
,3
]}

机构：

[1] Zhejiang Univ, Dept Hematol, Affiliated Hosp 1, Hangzhou 310003, Zhejiang, Peoples R China

[2] Yin Zhou People Hosp, Dept Hematol, Ningbo 315040, Zhejiang, Peoples R China

[3] Zhejiang Univ, Sch Med, Inst Hematol, Hangzhou 310009, Zhejiang, Peoples R China

[4] Zhejiang Univ, Dept Hepatobiliary & Pancreat Surg, Affiliated Hosp 1, Hangzhou 310003, Zhejiang, Peoples R China

[5] NINDS, Surg Neurol Branch, NIH, Bethesda, MD 20892 USA

[6] Zhejiang Univ, Sir Run Run Shaw Hosp, Dept Hematol, Hangzhou 310016, Zhejiang, Peoples R China

来源：

JOURNAL OF TRANSLATIONAL MEDICINE | 2014年 / 12卷

关键词：

ZOOM PROBLEM; ACUTE MYELOID-LEUKEMIA; CELL-LINE; DNA METHYLTRANSFERASE; SIGNALING PATHWAY; VALPROIC ACID; 5-AZA-2'-DEOXYCYTIDINE; DIFFERENTIATION; METHYLATION; CANCER; HYPERMETHYLATION;

D O I：

暂无

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页数：14

共 38 条

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