Lipids, cardiovascular disease and atherosclerosis in systemic lupus erythematosus

被引:22
作者
Wierzbicki, AS [1 ]
机构
[1] Kings Coll London, Guys Kings & St Thomas Med Sch, St Thomas Hosp, Dept Chem Pathol, London SE1 7EH, England
关键词
systemic lupus erythematosus; atherosclerosis; cardiovascular disease; lipids; apolipoproteins;
D O I
10.1191/096120300678828235
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Systemic lupus erythematosus is commonly associated with early onset cardiovascular disease and is often associated with hyperlipidaemia. This review examines the evidence for an increased prevalence of both CHD and hyperlipidaemia in SLE and mechanisms by which autoimmunity in SLE could accelerate the progression of atheroma. It postulates how lipid lowering therapies used in cardiological disease might help reduce the incidence of CHD in SLE.
引用
收藏
页码:194 / 201
页数:8
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