On-chip technologies for multidimensional separations

被引：38
作者：
Tia, Samuel [1 ]
Herr, Amy E. [1 ]
机构：
[1] Univ Calif Berkeley, Dept Bioengn, Berkeley, CA 94720 USA
来源：
LAB ON A CHIP | 2009年 / 9卷 / 17期
基金：
美国国家科学基金会;
关键词：
PERFORMANCE LIQUID-CHROMATOGRAPHY; TANDEM MASS-SPECTROMETRY; ELECTROKINETIC INJECTION TECHNIQUES; 2-DIMENSIONAL GEL-ELECTROPHORESIS; COLUMN-COUPLING CHIP; CAPILLARY-ELECTROPHORESIS; ZONE ELECTROPHORESIS; PROTEIN SEPARATIONS; INORGANIC ANIONS; HIGH-EFFICIENCY;
D O I：
10.1039/b900683b
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
We review microfluidic devices designed for multidimensional sample analysis, with a primer on relevant theory, an emphasis on protein analysis, and an eye towards future improvements and challenges to the field. Image shows results of an on-chip IEF-CE separation of a protein mixture; unpublished surface plot data from A. E. Herr.
引用
收藏
页码：2524 / 2536
页数：13
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