Biomaterials for bone tissue engineering scaffolds: a review

被引：557
作者：
Qu, Huawei [1 ]
Fu, Hongya [1 ]
Han, Zhenyu [1 ]
Sun, Yang [2 ]
机构：
[1] Harbin Inst Technol, Sch Mechatron Engn, Harbin 150001, Heilongjiang, Peoples R China
[2] Heilongjiang Univ Chinese Med, Sch Basic Med, Harbin 150030, Heilongjiang, Peoples R China
来源：
RSC ADVANCES | 2019年 / 9卷 / 45期
基金：
中国国家自然科学基金;
关键词：
MECHANICAL-PROPERTIES; BIOACTIVE GLASSES; COMPOSITE SCAFFOLDS; CALCIUM-SULFATE; IN-VITRO; HIERARCHICAL STRUCTURE; CERAMIC SCAFFOLDS; BMSCS CONSTRUCT; NANO-COMPOSITE; STROMAL CELLS;
D O I：
10.1039/c9ra05214c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Bone tissue engineering has been continuously developing since the concept of "tissue engineering" has been proposed. Biomaterials that are used as the basic material for the fabrication of scaffolds play a vital role in bone tissue engineering. This paper first introduces a strategy for literature search. Then, it describes the structure, mechanical properties and materials of natural bone and the strategies of bone tissue engineering. Particularly, it focuses on the current knowledge about biomaterials used in the fabrication of bone tissue engineering scaffolds, which includes the history, types, properties and applications of biomaterials. The effects of additives such as signaling molecules, stem cells, and functional materials on the performance of the scaffolds are also discussed.
引用
收藏
页码：26252 / 26262
页数：11
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