Motor symptoms in Parkinsonism and Parkinson's disease

被引：1
|
作者：
Grabli, David [1 ,2 ]
机构：
[1] Univ La Sorbonne, UPMC Paris 06, CNRS UMR 7225, UMR S 1127,Inst Cerveau & Moelle,Inserm 1127 & CI, 47-83,Blvd lHopital, F-75013 Paris, France
[2] AP HP, Hopital Pitie Salpetriere, Dept Malad Syst Nerveux, F-75013 Paris, France
来源：
PRESSE MEDICALE | 2017年 / 46卷 / 02期
关键词：
PROGRESSION;
D O I：
10.1016/j.lpm.2017.01.003
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Parkinsonian syndrome is the clinical expression of a lesion within the nigro-striatal dopaminergic pathway. Akinesia is the main manifestation of parkinsonism. The clinical analysis of motor symptoms may guide clinical diagnosis. Parkinson's disease is characterized by a pure asymmetric parkinsonian syndrome, responsive to dopaminergic treatment. The evolution of Parkinson's disease is characterized by the occurrence of motor complications (dyskinesia and fluctuations). Gait disturbances (postural instability and freezing) are late in Parkinson's disease. When early (within the first three years), they point to atypical parkinsonian syndrome.
引用
收藏
页码：187 / 194
页数：8
相关论文
共 50 条
  • [1] Functional Motor Symptoms in Parkinson's Disease and Functional Parkinsonism: A Systematic Review
    Akkaoui, Marine Ambar
    Geoffroy, Pierre A.
    Roze, Emmanuel
    Degos, Bertrand
    Garcin, Beatrice
    JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES, 2020, 32 (01) : 4 - 13
  • [2] Functional Motor Symptoms in Parkinson's Disease, and Functional Parkinsonism: A Systematic Review
    Akkaoui, M. Ambar
    Geoffroy, P.
    Roze, E.
    Degos, B.
    Garcin, B.
    MOVEMENT DISORDERS, 2019, 34 : S157 - S157
  • [3] Distribution of non-motor symptoms in idiopathic Parkinson's disease and secondary Parkinsonism
    Skogar, Orjan
    Nilsson, Mats
    JOURNAL OF MULTIDISCIPLINARY HEALTHCARE, 2018, 11 : 525 - 534
  • [4] NON MOTOR SYMPTOMS IN IDIOPATHIC PARKINSON'S DISEASE AND ATYPICAL PARKINSONISM - A COMPARATIVE ANALYSIS
    Grazynska, A.
    Antoniuk, S.
    Adamczewska, K.
    Bien, M.
    Siuda, J.
    PARKINSONISM & RELATED DISORDERS, 2020, 79 : E88 - E88
  • [5] Palliative Care and Nonmotor Symptoms in Parkinson's Disease and Parkinsonism
    Titova, Nataliya
    Chaudhuri, K. Ray
    NONMOTOR PARKINSON'S: THE HIDDEN FACE - MANAGEMENT AND THE HIDDEN FACE OF RELATED DISORDERS, 2017, 134 : 1239 - 1255
  • [6] Comparison of non-motor symptoms between drug induced parkinsonism and idiopathic Parkinson's disease
    Kim, J. S.
    Cho, J. W.
    Youn, J.
    Shin, H.
    MOVEMENT DISORDERS, 2012, 27 : S431 - S432
  • [7] Non motor symptoms Parkinson's disease
    Bagdanova, N.
    Zuleiha, Z.
    MOVEMENT DISORDERS, 2019, 34 : S623 - S623
  • [8] Progression of motor symptoms in Parkinson's disease
    Xia, Ruiping
    Mao, Zhi-Hong
    NEUROSCIENCE BULLETIN, 2012, 28 (01) : 39 - 48
  • [9] Treatment of motor symptoms in Parkinson's disease
    不详
    TIDSSKRIFT FOR DEN NORSKE LAEGEFORENING, 2023, 143 (07)
  • [10] Non motor symptoms in Parkinson's disease
    Rodriguez Quiroga, S. A.
    Christie, C.
    Diaz Arangunde, V.
    Mancuso, M.
    Arakaki, T.
    Toibaro, J.
    Garretto, N. S.
    MOVEMENT DISORDERS, 2012, 27 : S504 - S504
12345