CYP11A1 inhibition as a therapeutic approach for the treatment of castration resistant prostate cancer.

被引：3
|
作者：
Oksala, Riikka
Karimaa, Mari
Simola, Outi
Ramela, Meri
Riikonen, Reetta
Vehmaan-Kreula, Pirjo
Rummakko, Petteri
Wohlfahrt, Gerd
Kallio, Pekka
Mustonen, Mika V. J.
机构：
[1] Orion Corp Orion Pharma, Turku, Finland
[2] Orion Corp Orion Pharma, Espoo, Finland
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2018年 / 36卷 / 06期
关键词：
D O I：
10.1200/JCO.2018.36.6_suppl.340
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
340
引用
收藏
页数：1
相关论文
共 50 条
  • [1] CYP11A1 inhibition as a therapeutic approach for the treatment of castration resistant prostate cancer
    Oksala, R.
    Rasanen, K.
    Karimaa, M.
    Riikonen, R.
    Ramela, M.
    Vehmaan-Kreula, P.
    Simola, O.
    Rummakko, P.
    Wohlfahrt, G.
    Mustonen, M.
    ANNALS OF ONCOLOGY, 2018, 29
  • [2] Targeted Inhibition of CYP11A1 in Castration-Resistant Prostate Cancer
    St-Laurent, Marie-Pier
    Black, Peter C.
    EUROPEAN UROLOGY, 2024, 86 (02) : 185 - 186
  • [3] ODM-208, a novel CYP11A1-inhibitor as a therapeutic approach for the treatment of castration-resistant prostate cancer
    Oksala, R.
    Karimaa, M.
    Ramela, M.
    Riikonen, R.
    Huhtaniemi, R.
    Rummakko, P.
    Wohlfahrt, G.
    Vuorela, A.
    Mustonen, M. V.
    Kallio, P.
    ANNALS OF ONCOLOGY, 2017, 28
  • [4] Discovery of INV-9956, an orally available and highly selective Cyp11A1 inhibitor for the treatment of castration-resistant prostate cancer with drug resistant AR mutations
    Bai, Chang
    Chen, Danqi
    Xia, Zilei
    Huang, Shujuan
    Lin, LIshan
    Zeng, Zhaopie
    Su, Jing
    Sun, Yongkui
    CANCER RESEARCH, 2024, 84 (06)
  • [5] Inhibition and stimulation of activity of purified recombinant CYP11A1 by therapeutic agents
    Mast, Natalia
    Linger, Marlin
    Pikuleva, Irina A.
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2013, 371 (1-2) : 100 - 106
  • [6] EN3356, a novel CYP17A inhibitor for the treatment of castration resistant prostate cancer.
    Laping, Nicholas J.
    Sivanandhan, Dhanalakshmi
    Kethiri, Raghava Reddy
    Dewang, Purushottam M.
    Vijayendra, Ajith
    Zainuddin, Mohd
    Mullangi, Ramesh
    Rao, Niranjan
    Venkatesan, Aranapakam M.
    Reddy, Sanjeeva
    Gupta, Sandeep
    Smith, Roger A.
    MOLECULAR CANCER THERAPEUTICS, 2013, 12 (11)
  • [7] Targeting CYP11A1 as a potential therapeutic approach for renal cell carcinoma
    Ong, H. T. M.
    Kim, T. H.
    Ates, E.
    Pyun, J. C.
    Kang, M. J.
    MOLECULAR BIOLOGY OF THE CELL, 2023, 34 (02) : 568 - 569
  • [8] Therapeutic targeting of the p300/CBP bromodomain for the treatment of castration-resistant prostate cancer.
    Brooks, Nigel
    Pegg, Neil
    Worthington, Jenny
    Young, Barbara
    Prosser, Amy
    CANCER RESEARCH, 2018, 78 (16) : 74 - 75
  • [9] Limited in vitro efficacy of CYP17A1 inhibition on human castration resistant prostate cancer
    Kosaka, Takeo
    Miyajima, Akira
    Yasumizu, Yota
    Miyazaki, Yasumasa
    Kikuchi, Eiji
    Oya, Mototsugu
    STEROIDS, 2014, 92 : 39 - 44
  • [10] Novel approach to therapeutic targeting of castration-resistant prostate cancer
    Shankar, Eswar
    Franco, Daniel
    Iqbal, Omair
    El-Hayek, Victoria
    Gupta, Sanjay
    MEDICAL HYPOTHESES, 2020, 140
12345