Bioactive MIL-88A Framework Hollow Spheres via Interfacial Reaction In-Droplet Microfluidics for Enzyme and Nanoparticle Encapsulation

被引：134

作者：

Jeong, Guan-Young ^{[1
]}

Ricco, Raffaele ^{[2
]}

Liang, Kang ^{[2
]}

Ludwig, Johanna ^{[2
]}

Kim, Jin-Oh ^{[1
]}

Falcaro, Paolo ^{[2
]}

Kim, Dong-Pyo ^{[1
]}

机构：

[1] Pohang Univ Sci & Technol POSTECH, Dept Chem Engn, Pohang 790784, South Korea

[2] CSIRO, Mfg Flagship, Dickson, ACT 2602, Australia

来源：

CHEMISTRY OF MATERIALS | 2015年 / 27卷 / 23期

基金：

新加坡国家研究基金会;

关键词：

METAL-ORGANIC-FRAMEWORK; SELECTIVE OXIDATION; COMPOSITES; TEMPERATURE; IMMOBILIZATION; BIOCATALYSIS; DERIVATIVES; FLUORESCENT; PEROXIDASE; ULTRAFAST;

D O I：

10.1021/acs.chemmater.5b02847

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Functional bio-MOF hollow spheres with controlled size in the 35-2000 mu m range were successfully synthesized by interfacial reaction using a continuous-flow droplet microfluidic system in a single step and one-flow strategy. The architecture of MIL-88A frameworks was extended from single-shell to double-shell hollow spheres. Moreover, various functional nanopartides (silica, cobalt, and UiO-66(Zr) MOF) were directly encapsulated in the single-shell hollow spheres, while maintaining the functionality of the cargo. In particular, three kinds of enzymes (glycerol dehydrogenase, horseradish peroxidase, and acetylcholinesterase) were also encapsulated inside the single-shell hollow spheres under mild conditions. The catalytic activity and the superior recyclability of the encapsulated enzymes were demonstrated against free enzymes.

引用

页码：7903 / 7909

页数：7

共 51 条

[31] Facile and Sensitive Method for Detecting Cardiac Markers using Ubiquitous pH Meters [J].

Kwon, Donghoon ;

Joo, Jinmyoung ;

Lee, Sanghee ;

Jeon, Sangmin .

ANALYTICAL CHEMISTRY, 2013, 85 (24) :12134-12137

[32] Controllable synthesis of metal-organic framework hollow nanospheres by a versatile step-by-step assembly strategy [J].

Li, Ai-Ling ;

Ke, Fei ;

Qiu, Ling-Guang ;

Jiang, Xia ;

Wang, Yi-Min ;

Tian, Xing-You .

CRYSTENGCOMM, 2013, 15 (18) :3554-3559

[33] Biomimetic mineralization of metal-organic frameworks as protective coatings for biomacromolecules [J].

Liang, Kang ;

Ricco, Raffaele ;

Doherty, Cara M. ;

Styles, Mark J. ;

Bell, Stephen ;

Kirby, Nigel ;

Mudie, Stephen ;

Haylock, David ;

Hill, Anita J. ;

Doonan, Christian J. ;

Falcaro, Paolo .

NATURE COMMUNICATIONS, 2015, 6

[34] Immobilization of MP-11 into a Mesoporous Metal-Organic Framework, MP-11@mesoMOF: A New Platform for Enzymatic Catalysis [J].

Lykourinou, Vasiliki ;

Chen, Yao ;

Wang, Xi-Sen ;

Meng, Le ;

Tran Hoang ;

Ming, Li-June ;

Musselman, Ronald L. ;

Ma, Shengqian .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (27) :10382-10385

[35] One-Pot Synthesis of Protein-Embedded Metal-Organic Frameworks with Enhanced Biological Activities [J].

Lyu, Fengjiao ;

Zhang, Yifei ;

Zare, Richard N. ;

Ge, Jun ;

Liu, Zheng .

NANO LETTERS, 2014, 14 (10) :5761-5765

[36] An enzymatic process to α-ketoglutarate from L-glutamate:: the coupled system L-glutamate dehydrogenase/NADH oxidase [J].

Ödman, P ;

Wellborn, WB ;

Bommarius, AS .

TETRAHEDRON-ASYMMETRY, 2004, 15 (18) :2933-2937

[37] Ultrafast and Continuous Synthesis of Unaccommodating Inorganic Nanomaterials in Droplet- and Ionic Liquid-Assisted Microfluidic System [J].

Phan Huy Hoang ;

Park, HoSeok ;

Kim, Dong-Pyo .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (37) :14765-14770

[38] MOFs as proton conductors - challenges and opportunities [J].

Ramaswamy, Padmini ;

Wong, Norman E. ;

Shimizu, George K. H. .

CHEMICAL SOCIETY REVIEWS, 2014, 43 (16) :5913-5932

[39] Lead(II) uptake by aluminium based magnetic framework composites (MFCs) in water [J].

Ricco, Raffaele ;

Konstas, Kristina ;

Styles, Mark J. ;

Richardson, Joseph J. ;

Babarao, Ravichandar ;

Suzuki, Kiyonori ;

Scopece, Paolo ;

Falcaro, Paolo .

JOURNAL OF MATERIALS CHEMISTRY A, 2015, 3 (39) :19822-19831

[40] Applications of magnetic metal-organic framework composites [J].

Ricco, Raffaele ;

Malfatti, Luca ;

Takahashi, Masahide ;

Hill, Anita J. ;

Falcaro, Paolo .

JOURNAL OF MATERIALS CHEMISTRY A, 2013, 1 (42) :13033-13045

← 1 2 3 4 5 6 →