The mechanism of B-A transition in DNA molecule: Elastic interactions between sugars and nitrous bases

被引：0

作者：

Ponomarev, VO ^{[1
]}

Shikhovtseva, ES ^{[1
]}

机构：

[1] Russian Acad Sci, Ufa Res Ctr, Inst Phys Mol & Crystals, Ufa 450075, Russia

来源：

BIOFIZIKA | 2000年 / 45卷 / 01期

关键词：

DNA; molecule; B -> A transition; two-component model; soliton;

D O I：

暂无

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

A two-component model with elastic interactions between subsystems was proposed, which describes conformational transitions in the DNA molecule. The model is applicable for the description of B-->A transitions in the DNA molecule. It is shown that conformational excitations propagate along the macromolecule via stable topological solitons having a definite velocity. Two types of solitons can be distinguished: exciting and reducing. The exciting soliton realizes the transition of sugar from the ground state to a metastable state; in this process, the distance between complementary bases increases. The reducing soliton is formed behind the exciting soliton and realizes a reverse transition.

引用

页码：27 / 31

页数：5

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