Adherence to antiretroviral therapy, stigma and behavioral risk factors in HIV-infected adolescents in Asia

被引：15

作者：

Prasitsuebsai, Wasana ^{[1
]}

Sethaputra, Chuenkamol ^{[2
]}

Lumbiganon, Pagakrong ^{[3
]}

Hansudewechakul, Rawiwan ^{[4
]}

Chokephaibulkit, Kulkanya ^{[5
]}

Khanh Huu Truong ^{[6
]}

Lam Van Nguyen ^{[7
]}

Razali, Kamarul Azahar Mohd ^{[8
]}

Yusoff, Nik Khairulddin Nik ^{[9
]}

Fong, Moy Siew ^{[10
]}

Teeraananchai, Sirinya ^{[1
]}

Ananworanich, Jintanat ^{[11
,12
,13
,14
]}

Durier, Nicolas ^{[2
,15
]}

机构：

[1] Thai Red Cross AIDS Res Ctr, HIV Netherlands Australia Thailand Res Collaborat, Bangkok, Thailand

[2] TREAT Asia AmfAR, 388 Sukhumvit Rd,Suite 2104, Bangkok 10110, Klongtoey, Thailand

[3] Khon Kaen Univ, Srinagarind Hosp, Fac Med, Khon Kaen, Thailand

[4] Chiangrai Prachanukroh Hosp, Chiang Rai, Thailand

[5] Mahidol Univ, Fac Med, Siriraj Hosp, Bangkok, Thailand

[6] Childrens Hosp 1, Ho Chi Minh City, Vietnam

[7] Natl Hosp Pediat, Hanoi, Vietnam

[8] Hosp Kuala Lumpur, Inst Pediat, Kuala Lumpur, Malaysia

[9] Hosp Raja Perempuan Zainab II, Kelantan, Malaysia

[10] Hosp Likas, Kota Kinabalu, Malaysia

[11] Walter Reed Army Inst Res, US Mil HIV Res Program, Silver Spring, MD USA

[12] Henry M Jackson Fdn Adv Mil Med, Bethesda, MD USA

[13] Thai Red Cross AIDS Res Ctr, SEARCH, Bangkok, Thailand

[14] Univ Amsterdam, Amsterdam, Netherlands

[15] Dreamlopments LTD, Bangkok, Thailand

来源：

AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV | 2018年 / 30卷 / 06期

基金：

美国国家卫生研究院;

关键词：

HIV; adolescents; Asia; adherence; stigma; MEDICATION ADHERENCE; SOCIAL SUPPORT; DISCLOSURE; CHILDREN; THAILAND; YOUTH; IMPACT; MULTISITE; HIV/AIDS; COHORT;

D O I：

10.1080/09540121.2018.1425363

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

We studied behavioral risks among HIV-infected and uninfected adolescents using an audio computer-assisted self-interview. A prospective cohort study was initiated between 2013 and 2014 in Malaysia, Thailand, and Vietnam. HIV-infected adolescents were matched to uninfected adolescents (4:1) by sex and age group (12-14 and 15-18 years). We enrolled 250 HIV-infected (48% male; median age 14.5 years; 93% perinatally infected) and 59 uninfected (51% male; median age 14.1 years) adolescents. At enrollment, HIV-infected adolescents were on antiretroviral therapy (ART) for a median (IQR) of 7.5 (4.7-10.2) years, and 14% had HIV-RNA >1000copies/mL; 19% reported adherence <80%. Eighty-four (34%) HIV-infected and 26 (44%) uninfected adolescents reported having ever smoked cigarettes or drunk alcohol (p=0.13); 10% of HIV-infected and 17% of uninfected adolescents reported having initiated sexual activity; 6 of the HIV-infected adolescents had HIV-RNA >1000copies/mL. Risk behaviors were common among adolescents, with few differences between those with and without HIV.

引用

页码：727 / 733

页数：7

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