Adherence to antiretroviral therapy, stigma and behavioral risk factors in HIV-infected adolescents in Asia

被引：15

作者：

Prasitsuebsai, Wasana ^{[1
]}

Sethaputra, Chuenkamol ^{[2
]}

Lumbiganon, Pagakrong ^{[3
]}

Hansudewechakul, Rawiwan ^{[4
]}

Chokephaibulkit, Kulkanya ^{[5
]}

Khanh Huu Truong ^{[6
]}

Lam Van Nguyen ^{[7
]}

Razali, Kamarul Azahar Mohd ^{[8
]}

Yusoff, Nik Khairulddin Nik ^{[9
]}

Fong, Moy Siew ^{[10
]}

Teeraananchai, Sirinya ^{[1
]}

Ananworanich, Jintanat ^{[11
,12
,13
,14
]}

Durier, Nicolas ^{[2
,15
]}

机构：

[1] Thai Red Cross AIDS Res Ctr, HIV Netherlands Australia Thailand Res Collaborat, Bangkok, Thailand

[2] TREAT Asia AmfAR, 388 Sukhumvit Rd,Suite 2104, Bangkok 10110, Klongtoey, Thailand

[3] Khon Kaen Univ, Srinagarind Hosp, Fac Med, Khon Kaen, Thailand

[4] Chiangrai Prachanukroh Hosp, Chiang Rai, Thailand

[5] Mahidol Univ, Fac Med, Siriraj Hosp, Bangkok, Thailand

[6] Childrens Hosp 1, Ho Chi Minh City, Vietnam

[7] Natl Hosp Pediat, Hanoi, Vietnam

[8] Hosp Kuala Lumpur, Inst Pediat, Kuala Lumpur, Malaysia

[9] Hosp Raja Perempuan Zainab II, Kelantan, Malaysia

[10] Hosp Likas, Kota Kinabalu, Malaysia

[11] Walter Reed Army Inst Res, US Mil HIV Res Program, Silver Spring, MD USA

[12] Henry M Jackson Fdn Adv Mil Med, Bethesda, MD USA

[13] Thai Red Cross AIDS Res Ctr, SEARCH, Bangkok, Thailand

[14] Univ Amsterdam, Amsterdam, Netherlands

[15] Dreamlopments LTD, Bangkok, Thailand

来源：

AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV | 2018年 / 30卷 / 06期

基金：

美国国家卫生研究院;

关键词：

HIV; adolescents; Asia; adherence; stigma; MEDICATION ADHERENCE; SOCIAL SUPPORT; DISCLOSURE; CHILDREN; THAILAND; YOUTH; IMPACT; MULTISITE; HIV/AIDS; COHORT;

D O I：

10.1080/09540121.2018.1425363

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

We studied behavioral risks among HIV-infected and uninfected adolescents using an audio computer-assisted self-interview. A prospective cohort study was initiated between 2013 and 2014 in Malaysia, Thailand, and Vietnam. HIV-infected adolescents were matched to uninfected adolescents (4:1) by sex and age group (12-14 and 15-18 years). We enrolled 250 HIV-infected (48% male; median age 14.5 years; 93% perinatally infected) and 59 uninfected (51% male; median age 14.1 years) adolescents. At enrollment, HIV-infected adolescents were on antiretroviral therapy (ART) for a median (IQR) of 7.5 (4.7-10.2) years, and 14% had HIV-RNA >1000copies/mL; 19% reported adherence <80%. Eighty-four (34%) HIV-infected and 26 (44%) uninfected adolescents reported having ever smoked cigarettes or drunk alcohol (p=0.13); 10% of HIV-infected and 17% of uninfected adolescents reported having initiated sexual activity; 6 of the HIV-infected adolescents had HIV-RNA >1000copies/mL. Risk behaviors were common among adolescents, with few differences between those with and without HIV.

引用

页码：727 / 733

页数：7

共 34 条

[1]

[Anonymous], 2008, GLOBAL CONSULTATION

[2] A Comparison of Audio Computer-Assisted Self-Interviews to Face-to-Face Interviews of Sexual Behavior Among Perinatally HIV-Exposed Youth [J].

Dolezal, Curtis ;

Marhefka, Stephanie L. ;

Santamaria, E. Karina ;

Leu, Cheng-Shiun ;

Brackis-Cott, Elizabeth ;

Mellins, Claude Ann .

ARCHIVES OF SEXUAL BEHAVIOR, 2012, 41 (02) :401-410

[3] Individual and Contextual Factors of Sexual Risk Behavior in Youth Perinatally Infected with HIV [J].

Elkington, Katherine S. ;

Bauermeister, Jose A. ;

Robbins, Reuben N. ;

Gromadzka, Olga ;

Abrams, Elaine J. ;

Wiznia, Andrew ;

Bamji, Mahrukh ;

Mellins, Claude A. .

AIDS PATIENT CARE AND STDS, 2012, 26 (07) :411-422

[4] Perceptions of Audio Computer-Assisted Self-Interviewing (ACASI) among Women in an HIV-Positive Prevention Program [J].

Estes, Larissa J. ;

Lloyd, Linda E. ;

Teti, Michelle ;

Raja, Sheela ;

Bowleg, Lisa ;

Allgood, Kristi L. ;

Glick, Nancy .

PLOS ONE, 2010, 5 (02)

[5] Evidence for scale up: the differentiated care research agenda [J].

Grimsrud, Anna ;

Barnabas, Ruanne V. ;

Ehrenkranz, Peter ;

Ford, Nathan .

JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2017, 20

[6] Benefits of Disclosure of HIV Status to Infected Children and Adolescents: Perceptions of Caregivers and Health Care Providers [J].

Gyamfi, Eric ;

Okyere, Paul ;

Appiah-Brempong, Emmanuel ;

Adjei, Rose Odotei ;

Mensah, Kofi Akohene .

JANAC-JOURNAL OF THE ASSOCIATION OF NURSES IN AIDS CARE, 2015, 26 (06) :770-780

[7] Differences in young people's reports of sexual behaviors according to interview methodology: A randomized trial in India [J].

Jaya ;

Hindin, Michelle J. ;

Ahmed, Saifuddin .

AMERICAN JOURNAL OF PUBLIC HEALTH, 2008, 98 (01) :169-174

[8] Cohort Profile: The TREAT Asia Pediatric HIV Observational Database [J].

Kariminia, Azar ;

Chokephaibulkit, Kulkanya ;

Pang, Joselyn ;

Lumbiganon, Pagakrong ;

Hansudewechakul, Rawiwan ;

Amin, Janaki ;

Kumarasamy, Nagalingeswaran ;

Puthanakit, Thanyawee ;

Kurniati, Nia ;

Yusoff, Nik Khairulddin Nik ;

Saphonn, Vonthanak ;

Fong, Siew Moy ;

Razali, Kamarul ;

Nallusamy, Revathy ;

Sohn, Annette H. ;

Sirisanthana, Virat .

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2011, 40 (01) :15-24

[9] Impact of Internalized Stigma on HIV Prevention Behaviors Among HIV-Infected Individuals Seeking HIV Care in Kenya [J].

Kingori, Caroline ;

Reece, Michael ;

Obeng, Samuel ;

Murray, Maresa ;

Shacham, Enbal ;

Dodge, Brian ;

Akach, Emannuel ;

Ngatia, Peter ;

Ojakaa, David .

AIDS PATIENT CARE AND STDS, 2012, 26 (12) :761-768

[10] How you ask really matters: randomised comparison of four sexual behaviour questionnaire delivery modes in Zimbabwean youth [J].

Langhaug, Lisa F. ;

Cheung, Yin Bun ;

Pascoe, Sophie J. S. ;

Chirawu, Petronella ;

Woelk, Godfrey ;

Hayes, Richard J. ;

Cowan, Frances M. .

SEXUALLY TRANSMITTED INFECTIONS, 2011, 87 (02) :165-173

← 1 2 3 4 →