Perinatal outcomes of patients who achieved pregnancy with a morphologically poor embryo via assisted reproductive technology

被引:11
作者
Nakagawa, Koji [1 ]
Ojiro, Yuko [1 ]
Nishi, Yayoi [1 ]
Sugiyama, Rie [1 ]
Motoyama, Hiroshi [1 ]
Sugiyama, Rikikazu [1 ]
机构
[1] Sugiyama Clin, Div Reprod Med, Setagaya Ku, Tokyo 1560041, Japan
关键词
ART; Newborn; Perinatal outcome; Poorembryo quality; CLEAVAGE-STAGE EMBRYOS; OVARIAN STIMULATION; SINGLETONS BORN; IN-VITRO; QUALITY; ASSOCIATION; BLASTOCYSTS; IMPACT; FROZEN;
D O I
10.1007/s00404-015-3815-x
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
To learn more about the perinatal outcomes of conception via the use of low-grade embryos, we evaluated the relationship between the status of transferred embryos and the resultant perinatal outcomes. A total of 340 patients who achieved pregnancy via ART treatment and consequently delivered in our clinic between April 2009 and March 2014 were recruited for this study. Patients were divided into two groups according to a morphological assessment of the transferred embryos, which relegated 79 patients into a poor-embryo group with the remainders (n = 261) placed into a good-embryo group. The mean maternal age for the poor-embryo group was 36.0 years, which was similar to the good-embryo group (36.8). In both groups, the percentages of fresh ET cycles were similar. The values for the mean birth weight and birth height of infants in the poor-embryo group were 3055 g and 50.3 cm, respectively, and there were no significant differences with the good-embryo group. The umbilical blood gas analysis in the poor-quality group was similar to that in the good-embryo group. There were no obvious major anomalies among the infants of either group. The perinatal outcomes of the poor-embryo group were comparable to those of the good-embryo group. Based on these results, we can provide qualified assurance for a normal perinatal outcome to patients who had no choice but to undergo embryo transfer with a poor-quality embryo.
引用
收藏
页码:183 / 188
页数:6
相关论文
共 26 条
  • [1] Effect of embryo quality on pregnancy outcome following single embryo transfer in women with a diminished egg reserve
    Check, Jerome H.
    Summers-Chase, Donna
    Yuan, Wei
    Horwath, Danya
    Wilson, Carrie
    [J]. FERTILITY AND STERILITY, 2007, 87 (04) : 749 - 756
  • [2] Smaller fetal size in singletons after infertility therapies: the influence of technology and the underlying infertility
    Cooper, Amber R.
    O'Neill, Kathleen E.
    Allsworth, Jenifer E.
    Jungheim, Emily S.
    Odibo, Anthony O.
    Gray, Diana L.
    Ratts, Valerie S.
    Moley, Kelle H.
    Odem, Randall R.
    [J]. FERTILITY AND STERILITY, 2011, 96 (05) : 1100 - 1106
  • [3] Embryo fragmentation in vitro and its impact on treatment and pregnancy outcome
    Ebner, T
    Yaman, C
    Moser, M
    Sommergruber, M
    Pölz, W
    Tews, G
    [J]. FERTILITY AND STERILITY, 2001, 76 (02) : 281 - 285
  • [4] A morphological and chromosomal study of blastocysts developing from morphologically suboptimal human pre-embryos compared with control blastocysts
    Hardarson, T
    Caisander, G
    Sjögren, A
    Hanson, C
    Hamberger, L
    Lundin, K
    [J]. HUMAN REPRODUCTION, 2003, 18 (02) : 399 - 407
  • [5] Impact of frozen-thawed single-blastocyst transfer on maternal and neonatal outcome: an analysis of 277,042 single-embryo transfer cycles from 2008 to 2010 in Japan
    Ishihara, Osamu
    Araki, Ryuichiro
    Kuwahara, Akira
    Itakura, Atsuo
    Saito, Hidekazu
    Adamson, G. David
    [J]. FERTILITY AND STERILITY, 2014, 101 (01) : 128 - 133
  • [6] Neonatal outcome and birth defects in 6623 singletons born following minimal ovarian stimulation and vitrified versus fresh single embryo transfer
    Kato, Osamu
    Kawasaki, Nami
    Bodri, Daniel
    Kuroda, Tomoko
    Kawachiya, Satoshi
    Kato, Keiichi
    Takehara, Yuji
    [J]. EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2012, 161 (01) : 46 - 50
  • [7] Developmental capacity of different morphological types of day 5 human morulae and blastocysts
    Kovacic, B
    Vlaisavljevic, V
    Reljic, M
    Cizek-Sajko, M
    [J]. REPRODUCTIVE BIOMEDICINE ONLINE, 2004, 8 (06) : 687 - 694
  • [8] Transfer of nonselected transferable day 3 embryos in low embryo producers
    Kung, FT
    Chang, SY
    Yang, CY
    Lin, YC
    Lan, KC
    Huang, LY
    Huang, FJ
    [J]. FERTILITY AND STERILITY, 2003, 80 (06) : 1364 - 1370
  • [9] Obstetric and perinatal outcomes in singleton pregnancies resulting from the transfer of blastocyst-stage versus cleavage-stage embryos generated through in vitro fertilization treatment: a systematic review and meta-analysis
    Maheshwari, Abha
    Kalampokas, Theodoros
    Davidson, Jill
    Bhattacharya, Siladitya
    [J]. FERTILITY AND STERILITY, 2013, 100 (06) : 1615 - +
  • [10] Preterm birth and low birth weight among in vitro fertilization singletons: A systematic review and meta-analyses
    McDonald, Sarah D.
    Han, Zhen
    Mulla, Sohail
    Murphy, Kellie E.
    Beyene, Joseph
    Ohlsson, Arne
    [J]. EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2009, 146 (02) : 138 - 148