Prominent Vascular and Perivascular Eosinophilic Infiltrates Heralding CNS Mycosis Fungoides

被引：1

作者：

Schowinsky, Jeffrey ^{[1
]}

Leppert, Michelle ^{[2
]}

Ney, Douglas ^{[3
]}

Kleinschmidt-DeMasters, B. K. ^{[1
,3
,4
]}

机构：

[1] Univ Colorado, Dept Pathol, Anschutz Med Campus,B216,12631 East 17th Ave, Aurora, CO 80045 USA

[2] Univ Colorado, Dept Med, Aurora, CO 80045 USA

[3] Univ Colorado, Dept Neurol, Aurora, CO 80045 USA

[4] Univ Colorado, Dept Neurosurg, Aurora, CO 80045 USA

来源：

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY | 2015年 / 74卷 / 10期

关键词：

Brain; Eosinophils; Mycosis fungoides; T-cell lymphoma; CENTRAL-NERVOUS-SYSTEM; INVOLVEMENT; BRAIN; DIAGNOSIS;

D O I：

10.1097/NEN.0000000000000245

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Brain parenchymal involvement of mycosis fungoides (MF) is very rare. This study reports a patient with known cutaneous MF (under treatment) who presented with a CNS syndrome and multiple brain lesions. Brain biopsy demonstrated massive eosinophilic infiltrates but no MF cells. Despite treatment, new lesions developed and the patient died. At autopsy, there was massive involvement MF cells, suggesting that the eosinophilic infiltrates presaged the severe involvement of the CNS by MF.

引用

页码：948 / 951

页数：4

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