Neuro-Behcet Disease Presenting With Acute Psychosis in an Adolescent

被引:11
作者
Patel, Puja [1 ,2 ]
Steinschneider, Mitchell [2 ,3 ]
Boneparth, Alexis [4 ,5 ]
Lantos, George [6 ]
机构
[1] Montefiore Med Ctr, Bronx, NY 10467 USA
[2] Jacobi Med Ctr, Dept Neurol, Bronx, NY USA
[3] Albert Einstein Coll Med, Bronx, NY 10467 USA
[4] Childrens Hosp Montefiore, Bronx, NY USA
[5] Jacobi Med Ctr, Dept Rheumatol, Bronx, NY USA
[6] Jacobi Med Ctr, Dept Radiol, Bronx, NY USA
关键词
neuro-Behcet disease; acute psychosis; cerebral venous thrombosis; childhood; anti-tumor necrosis factor-; NEUROLOGICAL INVOLVEMENT; CLINICAL CHARACTERISTICS; MANAGEMENT; PATTERNS; ONSET;
D O I
10.1177/0883073813504137
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Behcet disease is a systemic vasculitis of unknown etiology that can affect the neurologic system. Neuro-Behcet disease is not well defined in children and adolescents, and the diagnosis is difficult to make in this population as they often present with insufficient symptoms to meet diagnostic criteria. Psychiatric symptoms as the initial manifestation of neuro-Behcet disease has rarely been reported. We describe a 17-year-old boy who presented with acute psychosis and was subsequently diagnosed with neuro-Behcet disease. A rare combination of both cerebral venous thrombosis and parenchymal central nervous system involvement was identified by neuroimaging. Although treatment guidelines for neuro-Behcet disease are limited, the patient made demonstrative clinical and radiographic improvement with a combination of corticosteroids, anticoagulation, and immunosuppressants, including a tumor necrosis factor- (TNF) blocking agent.
引用
收藏
页码:NP86 / NP91
页数:6
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