New bromopyrrole alkaloid from the marine sponge Agelas wiedenmayeri

被引:32
作者
Assmann, M [1 ]
Lichte, E [1 ]
van Soest, RWM [1 ]
Köck, M [1 ]
机构
[1] Univ Amsterdam, Inst Systematiek & Ecol, Museum Zool, NL-1090 GT Amsterdam, Netherlands
关键词
D O I
10.1021/ol990664h
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] A detailed analysis of the chemical constituents of a specimen of Agelas wiedenmayeri (Alcolado, 1984) was performed. Four brominated alkaloids (1-4) were isolated and one was identified as a new bromopyrrole metabolite. The structure of the new compound, 1, was assigned using spectroscopic methods, Compounds 2 and 3, which are the major brominated metabolites, have been previously described from other Agelas sponges. The new compound, 1, may be a biosynthetic precursor for oroidin-like derivatives.
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页码:455 / 457
页数:3
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