Language dominance in mesial temporal lobe epilepsy: A functional transcranial Doppler sonography study of brain plasticity

被引:8
作者
Knake, Susanne [1 ]
Haag, Anja [1 ]
Pilgramm, Guido [1 ]
Dittmer, Christine [1 ]
Reis, Janine [1 ]
Assmann, Heike [1 ]
Oertel, Wolfgang H. [1 ]
Rosenow, Felix [1 ]
Hamer, Hajo M. [1 ]
机构
[1] Univ Marburg, Dept Neurol, Interdisciplinary Epilepsy Ctr, D-35033 Marburg, Germany
关键词
language; epilepsy; hippocampal sclerosis; presurgical diagnosis; Doppler; transcranial Doppler sonography;
D O I
10.1016/j.yebeh.2006.06.011
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Functional transcranial Doppler sonography was used to study hemispheric language dominance (HLD) in 24 right-handed patients with left temporal lobe epilepsy (TLE) and a structural lesion in the left temporal lobe and in 69 healthy controls. Twenty-five percent of the patients and 4% of controls showed atypical (right or bilateral) HLD. Degree of HLD was not correlated with age, Full Scale IQ, Verbal IQ, spike frequency, seizure frequency, age at seizure onset, or duration of TLE. Atypical HLD appears to be lesion-induced, independent of epilepsy characteristics. (C) 2006 Elsevier Inc. All rights reserved.
引用
收藏
页码:345 / 348
页数:4
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