A Gateway for Phylogenetic Analysis Powered by Grid Computing Featuring GARLI 2.0

被引：170

作者：

Bazinet, Adam L. ^{[1
]}

Zwickl, Derrick J. ^{[2
]}

Cummings, Michael P. ^{[1
]}

机构：

[1] Univ Maryland, Ctr Bioinformat & Computat Biol, College Pk, MD 20742 USA

[2] Univ Arizona, Dept Ecol & Evolutionary Biol, Tucson, AZ 85721 USA

来源：

SYSTEMATIC BIOLOGY | 2014年 / 63卷 / 05期

基金：

美国国家科学基金会;

关键词：

GARLI; gateway; grid computing; maximum likelihood; molecular evolution portal; phylogenetics; web service; EVOLUTION; LIBRARY; MOTHS;

D O I：

10.1093/sysbio/syu031

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We introduce molecularevolution. org, a publicly available gateway for high-throughput, maximum-likelihood phylogenetic analysis powered by grid computing. The gateway features a GARLI 2.0 web service that enables a user to quickly and easily submit thousands of maximum likelihood tree searches or bootstrap searches that are executed in parallel on distributed computing resources. The GARLI web service allows one to easily specify partitioned substitution models using a graphical interface, and it performs sophisticated post-processing of phylogenetic results. Although the GARLI web service has been used by the research community for over three years, here we formally announce the availability of the service, describe its capabilities, highlight new features and recent improvements, and provide details about how the grid system efficiently delivers high-quality phylogenetic results.

引用

页码：812 / 818

页数：7

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