A canine peripheral nerve sheath tumor including peripheral nerve fibers

被引:18
作者
Sawamoto, O [1 ]
Yamate, J
Kuwamura, M
Hagiwara, R
Kurisu, K
机构
[1] Osaka Prefecture Univ, Grad Sch Agr & Biol Sci, Dept Vet Pathol, Osaka 5998531, Japan
[2] Otsuka Pharmaceut Factory Inc, Naruto Res Inst, Tokushima 7728601, Japan
关键词
canine; peripheral nerve sheath tumor (PNST); schwannoma;
D O I
10.1292/jvms.61.1335
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Peripheral nerve sheath tumor was found in a 7-year-old male mongrel dog. The tumors were located in the right cheek subcutis and oral submucosa. Histologically, neoplastic cells were arranged in streaming bundles, occasionally interlacing bundles or whorls of elongated and spindle cells. Cellular atypia was poor and mitotic figures were rarely observed. Ultrastructurally, neoplastic cells had basement membrane, typical of Schwann cells. One bundle of normal peripheral nerve fibers and some myelinated axons were seen within the tumor tissues. Immunohistochemically, neoplastic cells reacted to vimentin, glial fibrillary acidic protein, S-100 protein and neuron specific enolase. In addition to the above immunoreactions, the included nerve fibers were positive for myelin basic protein and neurofilament protein. This paper also discusses immunohistochemical findings on differential diagnosis in comparison with those of canine hemangiopericytomas reported hitherto.
引用
收藏
页码:1335 / 1338
页数:4
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