The Fecal Microbiota in the Domestic Cat (Fells catus) Is Influenced by Interactions Between Age and Diet; A Five Year Longitudinal Study

被引:35
作者
Bermingham, Emma N. [1 ,2 ]
Young, Wayne [1 ,2 ,3 ]
Butowski, Christina F. [1 ,4 ]
Moon, Christina D. [5 ]
Maclean, Paul H. [6 ]
Rosendale, Douglas [7 ]
Cave, Nicholas J. [8 ]
Thomas, David G. [4 ]
机构
[1] AgResearch, Food Nutr & Hlth Team, Palmerston North, New Zealand
[2] High Value Nutr Natl Sci Challenge, Auckland, New Zealand
[3] Massey Univ, Riddet Inst, Palmerston North, New Zealand
[4] Massey Univ, Sch Agr & Environment, Palmerston North, New Zealand
[5] AgResearch, Rumen Microbiol Team, Palmerston North, New Zealand
[6] AgResearch, Bioinformat & Stat Team, Lincoln, New Zealand
[7] New Zealand Inst Plant & Food Res Ltd, Food Nutr & Hlth Grp, Food Ind Sci Ctr, Palmerston North, New Zealand
[8] Massey Univ, Sch Vet Sci, Palmerston North, New Zealand
来源
FRONTIERS IN MICROBIOLOGY | 2018年 / 9卷
关键词
dietary format; canned diet; kibbled diet; insulin sensitivity index; aging; carnivore; body composition; RISK-FACTORS; DIABETES-MELLITUS; PHYSICAL-ACTIVITY; FELINE OBESITY; GUT MICROBIOME; GLUCOSE; DOGS; CARBOHYDRATE; PREVALENCE; METABOLISM;
D O I
10.3389/fmicb.2018.01231
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In humans, aging is associated with changes in the gastrointestinal microbiota; these changes may contribute to the age-related increase in incidence of many chronic diseases, including Type 2 diabetes. The life expectancies of cats are increasing, and they are also exhibiting the same types of diseases. While there are some studies investigating the impacts of diets on gastrointestinal microbiota in young cats, the impacts of aging in older cats has not been explored. We followed a cohort of related kittens, maintained on two commercial diets (kibbled and canned) from weaning (8 weeks) to 5 years of age (260 weeks). We hypothesized that the long-term feeding of specific diet formats would (a) lead to microbial composition changes due to aging, (b) impact body composition, and (c) affect insulin sensitivity in the aging cat. We observed that both diet and age affected fecal microbial composition, and while age correlated with changes in body composition, diet had no effect on body composition. Similarly insulin sensitivity was not affected by age nor diet. 16S rRNA sequencing found unclassified Peptostreptococcaceae were prominent across all ages averaging 21.3% of gene sequence reads and were higher in cats fed canned diets (average of 25.7% of gene sequence reads, vs. 17.0% for kibble-fed cats). Age -related effects on body composition and insulin sensitivity may become apparent as the cats grow older; this study will continue to assess these parameters.
引用
收藏
页数:15
相关论文
共 58 条
[1]   Occurrence of ampicillin-resistant Enterococcus faecium carrying esp gene in pet animals: An upcoming threat for pet lovers [J].
Abdel-Moein, Khaled A. ;
El-Hariri, Mahmoud D. ;
Wasfy, Momtaz O. ;
Samir, Ahmed .
JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE, 2017, 9 :115-117
[2]  
[Anonymous], 2015, R LANG ENV STAT COMP
[3]  
Association of American Feed Control Officials, 2016, 2016 OFF PUBL
[4]   Age and body weight effects on glucose and insulin tolerance in colony cats maintained since weaning on high dietary carbohydrate [J].
Backus, R. C. ;
Cave, N. J. ;
Ganjam, V. K. ;
Turner, J. B. M. ;
Biourge, V. C. .
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION, 2010, 94 (06) :E318-E328
[5]   Relationship between serum leptin immunoreactivity and body fat mass as estimated by use of a novel gas-phase Fourier transform infrared spectroscopy deuterium dilution method in cats [J].
Backus, RC ;
Havel, PJ ;
Gingerich, RL ;
Rogers, QR .
AMERICAN JOURNAL OF VETERINARY RESEARCH, 2000, 61 (07) :796-801
[6]  
Banfield Pet Hospital, 2016, BANF STAT PET HLTH 2
[7]   Aging in cats: Common physical and functional changes [J].
Bellows, Jan ;
Center, Sharon ;
Daristotle, Leighann ;
Estrada, Amara H. ;
Flickinger, Elizabeth A. ;
Horwitz, Debra F. ;
Lascelles, B. Duncan X. ;
Lepine, Allan ;
Perea, Sally ;
Scherk, Margie ;
Shoveller, Anna K. .
JOURNAL OF FELINE MEDICINE AND SURGERY, 2016, 18 (07) :533-550
[8]   Seasonal and age effects on energy requirements in domestic short-hair cats (Felis catus) in a temperate environment [J].
Bermingham, E. N. ;
Weidgraaf, K. ;
Hekman, M. ;
Roy, N. C. ;
Tavendale, M. H. ;
Thomas, D. G. .
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION, 2013, 97 (03) :522-530
[9]   Key bacterial families (Clostridiaceae, Erysipelotrichaceae and Bacteroidaceae are related to the digestion of protein and energy in dogs [J].
Bermingham, Emma N. ;
Maclean, Paul ;
Thomas, David G. ;
Cave, Nicholas J. ;
Young, Wayne .
PEERJ, 2017, 5
[10]   Post-Weaning Diet Affects Faecal Microbial Composition but Not Selected Adipose Gene Expression in the Cat (Felis catus) [J].
Bermingham, Emma N. ;
Kittelmann, Sandra ;
Young, Wayne ;
Kerr, Katherine R. ;
Swanson, Kelly S. ;
Roy, Nicole C. ;
Thomas, David G. .
PLOS ONE, 2013, 8 (11)