In the recent years, vibrational spectroscopics (infrared and Raman spectroscopy) have been developed for all soils of analyses in microbiology. Important Features of these methods are the relative case with which measurements can be performed. Furthermore, in order to obtain infrared or Raman spectra, there is only a limited amount of sample handling involved without the need for expensive chemicals, labels or dyes. Here, we review the potential application of vibrational spectroscopics for the use in medical microbiology. After describing some of the basics of the techniques, considerations on reproducibility and standardisation are presented. Finally, the use of infrared and Raman spectroscopy for the (rapid) identification of medically relevant microorganisms is discussed. It can be concluded that vibrational spectroscopics show high potential as novel methods in medical microbiology. (C) 2002 Published by Elsevier Science B.V.
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Univ Manchester, Manchester Inst Biotechnol, Sch Chem, Manchester, Lancs, EnglandUniv Manchester, Manchester Inst Biotechnol, Sch Chem, Manchester, Lancs, England
Muhamadali, Howbeer
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Subaihi, Abdu
Mohammadtaheri, Mahsa
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RMIT Univ, Ian Potter NanoBioSensing Facil, NanoBiotechnol Res Lab, Sch Sci, Melbourne, Vic, AustraliaUniv Manchester, Manchester Inst Biotechnol, Sch Chem, Manchester, Lancs, England
Mohammadtaheri, Mahsa
Xu, Yun
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Univ Manchester, Manchester Inst Biotechnol, Sch Chem, Manchester, Lancs, EnglandUniv Manchester, Manchester Inst Biotechnol, Sch Chem, Manchester, Lancs, England
Xu, Yun
Ellis, David I.
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Univ Manchester, Manchester Inst Biotechnol, Sch Chem, Manchester, Lancs, EnglandUniv Manchester, Manchester Inst Biotechnol, Sch Chem, Manchester, Lancs, England
Ellis, David I.
Ramanathan, Rajesh
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RMIT Univ, Ian Potter NanoBioSensing Facil, NanoBiotechnol Res Lab, Sch Sci, Melbourne, Vic, AustraliaUniv Manchester, Manchester Inst Biotechnol, Sch Chem, Manchester, Lancs, England
Ramanathan, Rajesh
Bansal, Vipul
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RMIT Univ, Ian Potter NanoBioSensing Facil, NanoBiotechnol Res Lab, Sch Sci, Melbourne, Vic, AustraliaUniv Manchester, Manchester Inst Biotechnol, Sch Chem, Manchester, Lancs, England
Bansal, Vipul
Goodacre, Royston
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Univ Manchester, Manchester Inst Biotechnol, Sch Chem, Manchester, Lancs, EnglandUniv Manchester, Manchester Inst Biotechnol, Sch Chem, Manchester, Lancs, England
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Washington Univ, Sch Med, Dept Pathol & Immunol, Div Lab & Genom Med, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Pathol & Immunol, Div Lab & Genom Med, St Louis, MO 63110 USA
Pence, M. A.
TeKippe, E. McElvania
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Washington Univ, Sch Med, Dept Pathol & Immunol, Div Lab & Genom Med, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Pathol & Immunol, Div Lab & Genom Med, St Louis, MO 63110 USA
TeKippe, E. McElvania
Wallace, M. A.
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Washington Univ, Sch Med, Dept Pathol & Immunol, Div Lab & Genom Med, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Pathol & Immunol, Div Lab & Genom Med, St Louis, MO 63110 USA
Wallace, M. A.
Burnham, C. -A. D.
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Washington Univ, Sch Med, Dept Pathol & Immunol, Div Lab & Genom Med, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Pathol & Immunol, Div Lab & Genom Med, St Louis, MO 63110 USA