Chiral tetraoxacalix[2]arene[2]triazine-based organocatalysts for Enantioselective Aldol reactions

被引：10
|
作者：
Genc, Hayriye Nevin [1 ]
Ozgun, Ummu [2 ]
Sirit, Abdulkadir [2 ]
机构：
[1] Necmettin Erbakan Univ, AK Educ Fac, Dept Sci Educ, TR-42090 Konya, Turkey
[2] Necmettin Erbakan Univ, AK Educ Fac, Dept Chem, TR-42090 Konya, Turkey
来源：
TETRAHEDRON LETTERS | 2019年 / 60卷 / 27期
关键词：
Asymmetric synthesis; Organocatalysis; Aldol reaction; Stereoselectivity; ASYMMETRIC MICHAEL ADDITION; SEPARATIONS; RESOLUTION; CATALYSIS; ALDEHYDES;
D O I：
10.1016/j.tetlet.2019.05.051
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Novel efficient chiral tetraoxacalix[2]arene[2]triazine-based organocatalysts have been designed and synthesized from the reaction of tetraoxacalix[2]arene[2]triazine with R/S-phenylethylamine or R/S-1-naphthylethylamine for the Aldol reaction of acetone with aromatic aldehydes to furnish the Aldol adducts in 71-92% yields with excellent enantioselectivities (78-99%). (C) 2019 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1763 / 1768
页数：6
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