One-pot oxidative Groebke-Blackburn-Bienayme reaction of alcohols: using bio-supported and magnetically recyclable Fe2O3@cellulose and Fe2O3@cellulose-SO3H nanocomposites for the synthesis of 3-aminoimidazo[1,2-a]pyridines

被引：6

作者：

Shaabani, Ahmad ^{[1
]}

Nosrati, Hamed ^{[1
]}

Hezarkhani, Zeinab ^{[1
]}

Afshari, Ronak ^{[1
]}

机构：

[1] Shahid Beheshti Univ, Fac Chem, GC, POB 19396-4716, Tehran, Iran

来源：

MONATSHEFTE FUR CHEMIE | 2018年 / 149卷 / 08期

基金：

美国国家科学基金会;

关键词：

Cellulose; Bio-supported catalyst; Fe2O3@cellulose; Fe2O3@cellulose-SO3H; Magnetite nanoparticles; ONE-STEP SYNTHESIS; 3-COMPONENT SYNTHESIS; AEROBIC OXIDATION; CELLULOSE; DERIVATIVES; NANOPARTICLES; IMIDAZOLE; PYRAZINES; PYRIDINES;

D O I：

10.1007/s00706-018-2182-2

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

One-pot oxidative Groebke-Blackburn-Bienayme three-component reaction has been successfully developed with primary alcohols instead of their corresponding aldehydes in the presence of recyclable Fe2O3@cellulose and Fe2O3@cellulose-SO3H catalysts. In this work, an efficient protocol for the oxidative synthesis of 3-aminoimidazo[1,2-a]pyridines via an alcohol, 2-aminopyridine, and an isocyanide in excellent yields in the presence of a catalytic amount of Fe2O3@cellulose or Fe2O3@cellulose-SO3H as magnetically recoverable heterogeneous catalysts is described. The reaction workup is simple and the catalysts can be easily magnetically separated from the reaction medium and reused in subsequent reactions. [GRAPHICS] .

引用

页码：1459 / 1467

页数：9

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