Modelling complex pathways between late-life depression and disability: evidence for mediating and moderating factors

被引:16
作者
Carriere, I. [1 ,2 ]
Villebrun, D. [2 ]
Peres, K. [3 ,4 ]
Stewart, R. [5 ]
Ritchie, K. [2 ]
Ancelin, M. L. [2 ]
机构
[1] Hop La Colombiere, INSERM, U888, F-34093 Montpellier 5, France
[2] Univ Montpellier 1, F-34006 Montpellier, France
[3] INSERM, U897, Bordeaux, France
[4] Univ Victor Segalen Bordeaux 2, Bordeaux, France
[5] Kings Coll London, Inst Psychiat, London, England
关键词
Aged; depression; disability evaluation; longitudinal studies; FUNCTIONAL LIMITATIONS; FUTURE-RESEARCH; OLDER-PEOPLE; RISK-FACTORS; SYMPTOMS; COMMUNITY; DECLINE; ADULTS;
D O I
10.1017/S0033291709005273
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Previous research has consistently shown an association between depression and disability in the elderly but little is known about the mechanisms linking the two. Recent longitudinal population Studies have shown considerable inconsistency in the criteria used to establish causality and terms such as mediation and effect modification have been frequently applied incorrectly in terms of the inferences drawn. We underline the necessity to adopt more stringent theoretical criteria for the establishment of intermediary effects in the relationship between depression and disability to better identify cross-validated potential intervention points for reducing the risk of disablement and depression.
引用
收藏
页码:1587 / 1590
页数:4
相关论文
共 14 条
[1]   Prevalence and risk factors for depression in a longitudinal, population-based study including individuals in the community and residential care [J].
Anstey, Kaarin J. ;
von Sanden, Chwee ;
Sargent-Cox, Kerry ;
Luszcz, Mary A. .
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 2007, 15 (06) :497-505
[2]  
Blazer DG, 2003, J GERONTOL A-BIOL, V58, P249
[3]   Depression and disability in late life -: Directions for future research [J].
Bruce, ML .
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 2001, 9 (02) :102-112
[4]   The longitudinal effect of depression on functional limitations and disability in older adults: an eight-wave prospective community-based study [J].
Geerlings, SW ;
Beekman, ATF ;
Deeg, DJH ;
Twisk, JWR ;
Van Tilburg, W .
PSYCHOLOGICAL MEDICINE, 2001, 31 (08) :1361-1371
[5]   How do risk factors work together? Mediators, moderators, and independent, overlapping, and proxy risk factors [J].
Kraemer, HC ;
Stice, E ;
Kazdin, A ;
Offord, D ;
Kupfer, D .
AMERICAN JOURNAL OF PSYCHIATRY, 2001, 158 (06) :848-856
[6]   How and why criteria defining moderators and mediators differ between the Baron & Kenny and MacArthur approaches [J].
Kraemer, Helena Chmura ;
Kiernan, Michaela ;
Essex, Marilyn ;
Kupfer, David J. .
HEALTH PSYCHOLOGY, 2008, 27 (02) :S101-S108
[7]   The course of functional decline in older people with persistently elevated depressive symptoms: Longitudinal findings from the cardiovascular health study [J].
Lenze, EJ ;
Schulz, R ;
Martire, LM ;
Zdaniuk, B ;
Glass, T ;
Kop, WJ ;
Jackson, SA ;
Reynolds, CF .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2005, 53 (04) :569-575
[8]   The association of late-life depression and anxiety with physical disability -: A review of the literature and prospectus for future research [J].
Lenze, EJ ;
Rogers, JC ;
Martire, LM ;
Mulsant, BH ;
Rollman, BL ;
Dew, MA ;
Schulz, R ;
Reynolds, CF .
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 2001, 9 (02) :113-135
[9]   Cognitive impairment, depressive symptoms, and functional decline in older people [J].
Mehta, KM ;
Yaffe, K ;
Covinsky, KE .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2002, 50 (06) :1045-1050
[10]   Gender differences in depression - Critical review [J].
Piccinelli, M ;
Wilkinson, G .
BRITISH JOURNAL OF PSYCHIATRY, 2000, 177 :486-492