Glucose Transporter 3 and 1 may Facilitate High Uptake of 18F-FDG in Gastric Schwannoma

被引：24

作者：

Shimada, Yutaka ^{[1
]}

Sawada, Shigeaki ^{[1
]}

Hojo, Shozo ^{[1
]}

Okumura, Tomoyuki ^{[1
]}

Nagata, Takuya ^{[1
]}

Nomoto, Kazuhiro ^{[2
]}

Tsukada, Kazuhiro ^{[1
]}

机构：

[1] Toyama Univ, Grad Sch Med & Pharmaceut Sci Res, Dept Surg & Sci, Toyama 9300194, Japan

[2] Toyama Univ, Grad Sch Med & Pharmaceut Sci Res, Dept Pathol, Toyama 9300194, Japan

来源：

CLINICAL NUCLEAR MEDICINE | 2013年 / 38卷 / 11期

关键词：

gastric schwannoma; F-18-FDG; glucose transporter; INCREASED FLUORODEOXYGLUCOSE UPTAKE; SQUAMOUS-CELL CARCINOMA; FDG ACCUMULATION; EXPRESSION; GLUT-1; PET; CANCER; TUMORS; PROTEINS;

D O I：

10.1097/RLU.0b013e318279f0d9

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Recently, some gastric schwannomas have been reported to have high uptake of FDG. However, Glut-1 was reported to be negative in gastric schwannomas tested. A 64-year-old female patient received a laparoscopic partial gastrectomy for a FDG PET-positive submucosal tumor (SUVmax 6.61). The resected tumor was diagnosed as a benign gastric schwannoma. Glut family immunohistochemical examination revealed diffuse positive expression of Glut-3 and partial positive expression of Glut-1. On the other hand, Glut-2 and Glut-4 expression in the tumor were negative. This case suggested that Glut-3 and Glut-1 expression were facilitators of high FDG uptake in the benign gastric schwannoma.

引用

页码：E417 / E420

页数：4

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