Evaluation of a real-time PCR assay for detection of Mycoplasma genitalium and macrolide resistance-mediating mutations from clinical specimens

被引：14

作者：

Xiao, Li ^{[1
]}

Waites, Ken B. ^{[2
]}

Wang, Hong ^{[3
]}

Van Der Pol, Barbara ^{[4
]}

Ratliff, Amy E. ^{[2
]}

Geisler, William M. ^{[4
]}

机构：

[1] Univ Alabama Birmingham, Dept Med, Div Clin Immunol & Rheumatol, Birmingham, AL 35294 USA

[2] Univ Alabama Birmingham, Dept Pathol, Birmingham, AL 35294 USA

[3] Univ Alabama Birmingham, Dept Pediat, Birmingham, AL USA

[4] Univ Alabama Birmingham, Dept Med, Div Infect Dis, Birmingham, AL 35294 USA

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2018年 / 91卷 / 02期

关键词：

Mycoplasma genitalium; Macrolide; Resistance; Real-time PCR; IDENTIFICATION;

D O I：

10.1016/j.diagmicrobio.2018.02.002

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Mycoplasma genitalium (MG) is a sexually transmitted pathogen for which there is no FDA-approved diagnostic test available in the United States. A modified real-time polymerase chain reaction assay for detecting MG and simultaneously identifying macrolide resistance mutations from clinical specimens was evaluated and proved to be sensitive and accurate for diagnostic purposes. (C) 2018 Elsevier Inc. All rights reserved.

引用

页码：123 / 125

页数：3

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