Zoledronic acid-induced orbital inflammation in a patient with multiple myeloma

被引：7

作者：

Tan, Marisela ^{[1
]}

Kalin-Hajdu, Evan ^{[2
]}

Narayan, Rupa ^{[3
]}

Wong, Sandy W. ^{[3
]}

Martin, Thomas G. ^{[3
]}

机构：

[1] Univ Calif San Francisco, Dept Pharmaceut Serv, Div Hematol Oncol, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Dept Ophthalmol, Div Hematol Oncol, San Francisco, CA USA

[3] Univ Calif San Francisco, Dept Med, Div Hematol Oncol, 400 Parnassus Ave,Box 0324, San Francisco, CA 94143 USA

来源：

JOURNAL OF ONCOLOGY PHARMACY PRACTICE | 2019年 / 25卷 / 05期

关键词：

Zoledronic acid; bisphosphonate; orbital inflammation; multiple myeloma; DELTA T-CELLS; CASE SERIES; INFUSION; DISEASE; SCLERITIS; SECONDARY;

D O I：

10.1177/1078155218785967

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Multiple myeloma is a cancer of malignant plasma cells which stimulates osteoclasts and is associated with increased bone turnover and osteolysis. Bisphosphonates including zolendronic acid are used to prevent skeletal complications in patients with multiple myeloma. Orbital inflammation is a rare but serious complication following use of bisphosphonates. The diagnosis is made by excluding other possible causes in patients with myeloma and rapid initiation of therapy is required. Corticosteroids are the mainstay of therapy but the ideal treatment course has not been delineated. This report describes a case of this rare complication and provides a review of the literature.

引用

页码：1253 / 1257

页数：5

共 24 条

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