Freehand SPECT-guided sentinel lymph node biopsy in early oral squamous cell carcinoma

被引:20
|
作者
Bluemel, Christina [1 ]
Herrmann, Ken [1 ]
Mueller-Richter, Urs [2 ]
Lapa, Constantin [1 ]
Higuchi, Takahiro [1 ]
Wild, Vanessa [3 ]
Buck, Andreas K. [1 ]
Kuebler, Alexander [2 ]
Linz, Christian [2 ]
机构
[1] Univ Hosp Wurzburg, Dept Nucl Med, D-97080 Wurzburg, Germany
[2] Univ Hosp Wurzburg, Dept Oral & Maxillofacial Plast Surg, D-97080 Wurzburg, Germany
[3] Univ Wurzburg, Inst Pathol, Wurzburg, Germany
关键词
sentinel lymph node biopsy; squamous cell carcinoma; freehand single-photon emission CT (fhSPECT); head and neck cancer; neck dissection; SELECTIVE NECK DISSECTION; MULTICENTER TRIAL; BREAST-CANCER; HEAD; EXPERIENCE;
D O I
10.1002/hed.23596
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
BackgroundIn oral squamous cell carcinoma (OSCC), cervical lymph node status is the most important prognostic factor. Compared to elective neck dissection, reduced morbidity and better quality of life was demonstrated for sentinel lymph node biopsy, which is controversial because of the reduced detection rate of sentinel lymph nodes in close proximity to the injection site (also known as the shine-through phenomenon). MethodsWe report the case of a 44-year-old woman with a biopsy-proven early OSCC of the anterior floor of the mouth, who received SLNB guided with freehand single-photon emission CT (fhSPECT), a system for the 3D visualization of radioactivity in the body. ResultsOne level III sentinel lymph node and 1 level I sentinel lymph node, in close proximity to the injection site, were detected and dissected. The level I sentinel lymph node contained a metastasis. ConclusionUsing fhSPECT, the issue outlined was overcome, and the precise histopathological lymph node status (pN1; 1 of 49) was determined. (c) 2014 Wiley Periodicals, Inc. Head Neck 36: E112-E116, 2014
引用
收藏
页码:E112 / E116
页数:5
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