Anti-neutrophil cytoplasm autoantibodies (ANCA) in autoimmune liver diseases

被引：0

作者：

Roozendaal, C ^{[1
]}

Kallenberg, CGM ^{[1
]}

机构：

[1] Univ Groningen Hosp, Dept Clin Immunol, NL-9700 RB Groningen, Netherlands

来源：

HEPATO-GASTROENTEROLOGY | 1999年 / 46卷 / 30期

关键词：

autoimmune liver disease; anti-neutrophil cytoplasm antibodies; primary sclerosing cholangitis; autoimmune hepatitis; primary biliary cirrhosis; autoantigens;

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Anti-neutrophil cytoplasm antibodies (ANCA) are autoantibodies directed against cytoplasmic constituents of neutrophil granulocytes and monocytes. ANCA have been detected in serum from patients with inflammatory bowel diseases (mainly ulcerative colitis) and autoimmune mediated liver diseases (mainly primary sclerosing cholangitis and autoimmune hepatitis-type 1). The antigens recognized by ANCA in these diseases are multiple and the clinical and pathophysiological significance of ANCA in these disorders has not been completely defined.

引用

页码：3034 / 3040

页数：7

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