Enhanced dynamic range x-ray imaging

被引:16
作者
Haidekker, Mark A. [1 ]
Morrison, Logan Dain-Kelley [1 ]
Sharma, Ajay [2 ]
Burke, Emily [2 ]
机构
[1] Univ Georgia, Coll Engn, Driftmier Engn Ctr, 597 DW Brooks Dr, Athens, GA 30602 USA
[2] Univ Georgia, Coll Vet Med, Athens, GA 30602 USA
关键词
X-ray absorption; Saturation; Contrast; Dynamic range; Noise; PHASE-CONTRAST; RADIOGRAPHY; SYSTEM;
D O I
10.1016/j.compbiomed.2017.01.014
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
X-ray images can suffer from excess contrast. Often, image exposure is chosen to visually optimize the region of interest, but at the expense of over- and underexposed regions elsewhere in the image. When image values are interpreted quantitatively as projected absorption, both over- and underexposure leads to the loss of quantitative information. We propose to combine multiple exposures into a composite that uses only pixels from those exposures in which they are neither under- nor overexposed. The composite image is created in analogy to visible-light high dynamic range photography. We present the mathematical framework for the recovery of absorbance from such composite images and demonstrate the method with biological and non biological samples. We also show with an aluminum step-wedge that accurate recovery of step thickness from the absorbance values is possible, thereby highlighting the quantitative nature of the presented method. Due to the higher amount of detail encoded in an enhanced dynamic range x-ray image, we expect that the number of retaken images can be reduced, and patient exposure overall reduced. We also envision that the method can improve dual energy absorptiometry and even computed tomography by reducing the number of low-exposure ("photon-starved") projections.
引用
收藏
页码:40 / 48
页数:9
相关论文
共 20 条
  • [1] [Anonymous], 2002, Computational Methods for Inverse Problems
  • [2] The dynamic range of digital radiographic systems: dose reduction or risk of overexposure?
    Berkhout, WER
    Beuger, DA
    Sanderink, GCH
    van der Stelt, PF
    [J]. DENTOMAXILLOFACIAL RADIOLOGY, 2004, 33 (01) : 1 - 5
  • [3] On the noise variance of a digital mammography system
    Burgess, A
    [J]. MEDICAL PHYSICS, 2004, 31 (07) : 1987 - 1995
  • [4] Bushberg JerroldT., 2002, ESSENTIAL PHYS MED I
  • [5] Patient-based radiographic exposure factor selection: a systematic review
    Ching, William
    Robinson, John
    McEntee, Mark
    [J]. JOURNAL OF MEDICAL RADIATION SCIENCES, 2014, 61 (03): : 176 - 190
  • [6] Development of a portable digital radiographic system based on FOP-coupled CMOS image sensor and its performance evaluation
    Cho, HS
    Jeong, MH
    Han, BS
    Kim, S
    Lee, BS
    Kim, HK
    Lee, SC
    [J]. IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2005, 52 (05) : 1766 - 1772
  • [7] Dual-Energy Technique at Low Tube Voltages for Small Animal Imaging
    Cho S.
    Sidky E.Y.
    Bian J.
    Pan X.
    [J]. Tsinghua Science and Technology, 2010, 15 (01) : 79 - 86
  • [8] Devlin K., CSTR02005 U BRIST
  • [9] Haidekker M.A., 2011, Advanced biomedical image analysis
  • [10] Hubbell JH, 1996, TABLES XRAY MASS ATT, DOI DOI 10.18434/T4D01F