Comment on "In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically-Based Absorption Models"

被引：8
|
作者：
Turner, David B. [1 ]
Liu, Bo [1 ]
Patel, Nikunjkumar [1 ]
Pathak, Shriram M. [1 ]
Polak, Sebastian [1 ,2 ]
Jamei, Masoud [1 ]
Dressman, Jennifer [4 ]
Rostami-Hodjegan, Amin [1 ,3 ]
机构：
[1] Simcyp Ltd, Blades Enterprise Ctr, John St, Sheffield S2 4SU, S Yorkshire, England
[2] Jagiellonian Univ, Coll Med, Fac Pharm, Krakow, Poland
[3] Univ Manchester, Manchester Pharm Sch, Manchester M13 9PT, Lancs, England
[4] Goethe Univ, Fac Biochem Chem & Pharm, Frankfurt, Germany
来源：
MOLECULAR PHARMACEUTICS | 2017年 / 14卷 / 01期
关键词：
FEXOFENADINE; BIOAVAILABILITY; VOLUMES; TRANSIT; HUMANS; VITRO; WATER;
D O I：
10.1021/acs.molpharmaceut.6b00469
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
引用
收藏
页码：336 / 339
页数：4
相关论文
共 50 条
  • [41] Use of Three-Compartment Physiologically Based Pharmacokinetic Modeling to Predict Hepatic Blood Levels of Fluvoxamine Relevant for Drug-Drug Interactions
    Iga, Katsumi
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2015, 104 (04) : 1478 - 1491
  • [42] SeDeM expert system with I-optimal mixture design for oral multiparticulate drug delivery: An encapsulated floating minitablets of loxoprofen Na and its in silico physiologically based pharmacokinetic modeling
    Rauf-ur-Rehman
    Shoaib, Muhammad Harris
    Ahmed, Farrukh Rafiq
    Yousuf, Rabia Ismail
    Siddiqui, Fahad
    Saleem, Muhammad Talha
    Qazi, Faaiza
    Khan, Momina Zarish
    Irshad, Asma
    Bashir, Lubna
    Naz, Shazia
    Farooq, Muhammad
    Mahmood, Zafar Alam
    FRONTIERS IN PHARMACOLOGY, 2023, 14
  • [43] Effect of Absorption Behavior of Solubilizers on Drug Dissolution in the Gastrointestinal Tract: Evaluation Based on In Vivo Luminal ConcentrationeTime Profile of Cilostazol, a Poorly Soluble Drug, and Solubilizers
    Tanaka, Yusuke
    Kubota, Atsuo
    Matsuo, Akira
    Kawakami, Ayaka
    Kamizi, Hiroki
    Mochigoe, Akane
    Hiramachi, Takahiro
    Kasaoka, Satoshi
    Yoshikawa, Hiroshi
    Nagata, Shunji
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2016, 105 (09) : 2825 - 2831
  • [44] Bioequivalence requirements for orally inhaled and nasal drug products and use of novel physiologically based biopharmaceutics modeling approaches for assessing in vivo performance
    Rachapally, Aravind
    Boddu, Rajkumar
    Kollipara, Sivacharan
    Ahmed, Tausif
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2025, 114 (02) : 701 - 718
  • [45] Justification of Drug Product Dissolution Rate and Drug Substance Particle Size Specifications Based on Absorption PBPK Modeling for Lesinurad Immediate Release Tablets
    Pepin, Xavier J. H.
    Flanagan, Talia R.
    Holt, David J.
    Eidelman, Anna
    Treacy, Don
    Rowlings, Colin E.
    MOLECULAR PHARMACEUTICS, 2016, 13 (09) : 3256 - 3269
  • [46] Comparison of Deconvolution-Based and Absorption Modeling IVIVC for Extended Release Formulations of a BCS III Drug Development Candidate
    Kesisoglou, Filippos
    Xia, Binfeng
    Agrawal, Nancy G. B.
    AAPS JOURNAL, 2015, 17 (06): : 1492 - 1500
  • [47] Towards More Robust Evaluation of the Predictive Performance of Physiologically Based Pharmacokinetic Models: Using Confidence Intervals to Support Use of Model-Informed Dosing in Clinical Care
    van Borselen, Marjolein D.
    Sluijterman, Laurens Auke Aemiel
    Greupink, Rick
    de Wildt, Saskia N.
    CLINICAL PHARMACOKINETICS, 2024, 63 (03) : 343 - 355
  • [48] Assessment of in Vivo Performance of Lipid-Based Formulations: Correlation between in Vitro Drug Release Profiles and in Vivo Absorption Rate Profiles
    Higashino, Haruki
    Masada, Takato
    Minami, Keiko
    Kataoka, Makoto
    Yamashita, Shinji
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2024, 47 (10) : 1616 - 1623
  • [49] Development and Evaluation of Cucurbitacin B Microemulsion: the Effect of Oil Phase and Aqueous Phase on Drug Percutaneous Absorption Based on ATR-FTIR Spectroscopy and Molecular Modeling
    Qi Tian
    Jianbo Guo
    Qi Zhang
    Liang Fang
    Chao Liu
    Hui Xu
    AAPS PharmSciTech, 21
  • [50] Development and Evaluation of Cucurbitacin B Microemulsion: the Effect of Oil Phase and Aqueous Phase on Drug Percutaneous Absorption Based on ATR-FTIR Spectroscopy and Molecular Modeling
    Tian, Qi
    Guo, Jianbo
    Zhang, Qi
    Fang, Liang
    Liu, Chao
    Xu, Hui
    AAPS PHARMSCITECH, 2020, 21 (07)
12345