Comment on "In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically-Based Absorption Models"

被引：8
|
作者：
Turner, David B. [1 ]
Liu, Bo [1 ]
Patel, Nikunjkumar [1 ]
Pathak, Shriram M. [1 ]
Polak, Sebastian [1 ,2 ]
Jamei, Masoud [1 ]
Dressman, Jennifer [4 ]
Rostami-Hodjegan, Amin [1 ,3 ]
机构：
[1] Simcyp Ltd, Blades Enterprise Ctr, John St, Sheffield S2 4SU, S Yorkshire, England
[2] Jagiellonian Univ, Coll Med, Fac Pharm, Krakow, Poland
[3] Univ Manchester, Manchester Pharm Sch, Manchester M13 9PT, Lancs, England
[4] Goethe Univ, Fac Biochem Chem & Pharm, Frankfurt, Germany
来源：
MOLECULAR PHARMACEUTICS | 2017年 / 14卷 / 01期
关键词：
FEXOFENADINE; BIOAVAILABILITY; VOLUMES; TRANSIT; HUMANS; VITRO; WATER;
D O I：
10.1021/acs.molpharmaceut.6b00469
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
引用
收藏
页码：336 / 339
页数：4
相关论文
共 50 条
  • [31] Physiologically Based Absorption Modeling to Design Extended-Release Clinical Products for an Ester Prodrug
    Ding, Xuan
    Day, Jeffrey S.
    Sperry, David C.
    AAPS JOURNAL, 2016, 18 (06): : 1424 - 1438
  • [32] Analysis of the impact of controlled release formulations on oral drug absorption, gut wall metabolism and relative bioavailability of CYP3A substrates using a physiologically-based pharmacokinetic model
    Olivares-Morales, Andres
    Kamiyama, Yoshiteru
    Darwich, Adam S.
    Aarons, Leon
    Rostami-Hodjegan, Amin
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2015, 67 : 32 - 44
  • [33] Evaluating the Impact of Physiological Properties of the Gastrointestinal Tract On Drug In Vivo Performance Using Physiologically Based Biopharmaceutics Modeling and Virtual Clinical Trials
    Jereb, Rebeka
    Opara, Jerneja
    Bajc, Aleksander
    Petek, Bostjan
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 110 (08) : 3069 - 3081
  • [34] Quantitative analysis of the effect of controlled -release formulation on nonlinear gastrointestinal absorption of P-glycoprotein substrate talinolol using physiologically based pharmacokinetic absorption model
    Suzuki, Satoru
    Shirasaka, Yoshiyuki
    Okada, Ren
    Eguchi, Akari
    Kishimoto, Hisanao
    Langguth, Peter
    Inoue, Katsuhisa
    JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2020, 56
  • [35] Predictive Performance of Next Generation Physiologically Based Kinetic (PBK) Model Predictions in Rats Based on In Vitro and In Silico Input Data
    Punt, Ans
    Louisse, Jochem
    Pinckaers, Nicole
    Fabian, Eric
    van Ravenzwaay, Bennard
    TOXICOLOGICAL SCIENCES, 2022, 186 (01) : 18 - 28
  • [36] The Antibody Drug Absorption Following Subcutaneous or Intramuscular Administration and Its Mathematical Description by Coupling Physiologically Based Absorption Process with the Conventional Compartment Pharmacokinetic Model
    Zhao, Liang
    Ji, Ping
    Li, Zhihong
    Roy, Partha
    Sahajwalla, Chandrahas G.
    JOURNAL OF CLINICAL PHARMACOLOGY, 2013, 53 (03) : 314 - 325
  • [37] Variance based global sensitivity analysis of physiologically based pharmacokinetic absorption models for BCS I-IV drugs
    Melillo, Nicola
    Aarons, Leon
    Magni, Paolo
    Darwich, Adam S.
    JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, 2019, 46 (01) : 27 - 42
  • [38] Application of Physiologically Based Absorption Modeling to Formulation Development of a Low Solubility, Low Permeability Weak Base: Mechanistic Investigation of Food Effect
    Zhang, Hefei
    Xia, Binfeng
    Sheng, Jennifer
    Heimbach, Tycho
    Lin, Tsu-Han
    He, Handan
    Wang, Yanfeng
    Novick, Steven
    Comfort, Ann
    AAPS PHARMSCITECH, 2014, 15 (02): : 400 - 406
  • [39] Application of Physiologically Based Absorption Modeling to Characterize the Pharmacokinetic Profiles of Oral Extended Release Methylphenidate Products in Adults
    Yang, Xiaoxia
    Duan, John
    Fisher, Jeffrey
    PLOS ONE, 2016, 11 (10):
  • [40] Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed Physiologically-Based Pharmacokinetic Model of Ritonavir Norvir Tablet Absorption in Humans Under Fasted and Fed State Conditions
    Arora, Sumit
    Pansari, Amita
    Kilford, Peter
    Jamei, Masoud
    Gardner, Iain
    Turner, David B.
    MOLECULAR PHARMACEUTICS, 2020, 17 (07) : 2329 - 2344
12345