Comment on "In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically-Based Absorption Models"

被引：8
|
作者：
Turner, David B. [1 ]
Liu, Bo [1 ]
Patel, Nikunjkumar [1 ]
Pathak, Shriram M. [1 ]
Polak, Sebastian [1 ,2 ]
Jamei, Masoud [1 ]
Dressman, Jennifer [4 ]
Rostami-Hodjegan, Amin [1 ,3 ]
机构：
[1] Simcyp Ltd, Blades Enterprise Ctr, John St, Sheffield S2 4SU, S Yorkshire, England
[2] Jagiellonian Univ, Coll Med, Fac Pharm, Krakow, Poland
[3] Univ Manchester, Manchester Pharm Sch, Manchester M13 9PT, Lancs, England
[4] Goethe Univ, Fac Biochem Chem & Pharm, Frankfurt, Germany
来源：
MOLECULAR PHARMACEUTICS | 2017年 / 14卷 / 01期
关键词：
FEXOFENADINE; BIOAVAILABILITY; VOLUMES; TRANSIT; HUMANS; VITRO; WATER;
D O I：
10.1021/acs.molpharmaceut.6b00469
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
引用
收藏
页码：336 / 339
页数：4
相关论文
共 50 条
  • [21] Using Physiologically Based Pharmacokinetic (PBPK) Modeling to Evaluate the Impact of Pharmaceutical Excipients on Oral Drug Absorption: Sensitivity Analyses
    Chow, Edwin Chiu Yuen
    Talattof, Arjang
    Tsakalozou, Eleftheria
    Fan, Jianghong
    Zhao, Liang
    Zhang, Xinyuan
    AAPS JOURNAL, 2016, 18 (06): : 1500 - 1511
  • [22] Application of physiologically based absorption and pharmacokinetic modeling in the development process of oral modified release generic products
    Subhani, Saima
    Kim, Chaejin
    Muniz, Paula
    Rodriguez, Monica
    van Os, Sandra
    Suarez, Elena
    Cristofoletti, Rodrigo
    Schmidt, Stephan
    Vozmediano, Valvanera
    EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2022, 176 : 87 - 94
  • [23] The Provisional No-Effect Threshold of Sugar Alcohols on Oral Drug Absorption Estimated by Physiologically Based Biopharmaceutics Model
    Yamane, Miki
    Matsui, Kazuki
    Sugihara, Masahisa
    Tokunaga, Yuji
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 110 (01) : 467 - 477
  • [24] Physiologically Based Oral Absorption Modelling to Study Gut-Level Drug Interactions
    Chung, John
    Kesisoglou, Filippos
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2018, 107 (01) : 18 - 23
  • [25] Predicting human exposure of active drug after oral prodrug administration, using a joined in vitro/in silico-in vivo extrapolation and physiologically-based pharmacokinetic modeling approach
    Malmborg, Jonas
    Ploeger, Bart A.
    JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2013, 67 (03) : 203 - 213
  • [26] Investigation of clinical pharmacokinetic variability of an opioid antagonist through physiologically based absorption modeling
    Ding, Xuan
    He, Minxia
    Kulkarni, Rajesh
    Patel, Nita
    Zhang, Xiaoyu
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2013, 102 (08) : 2859 - 2874
  • [27] Prediction of gastric pH-mediated drug exposure using physiologically-based pharmacokinetic modeling: A case study of itraconazole
    Yang, Eunsol
    Yu, Kyung-Sang
    Lee, SeungHwan
    CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 2023, 12 (06): : 865 - 877
  • [28] Predicting Human Pharmacokinetics: Physiologically Based Pharmacokinetic Modeling and In Silico ADME Prediction in Early Drug Discovery
    Shi, Jian
    Zha, Weibin
    EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2019, 44 (01) : 135 - 137
  • [29] Forecasting oral absorption across biopharmaceutics classification system classes with physiologically based pharmacokinetic models
    Hansmann, Simone
    Darwich, Adam
    Margolskee, Alison
    Aarons, Leon
    Dressman, Jennifer
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2016, 68 (12) : 1501 - 1515
  • [30] Evaluation of the predictive performance of physiologically based pharmacokinetic models for intramuscular injections of therapeutic proteins
    Chow, Timothy W.
    Wright, Matthew R.
    Hop, Cornelis E. C. A.
    Wong, Harvey
    XENOBIOTICA, 2019, 49 (12) : 1423 - 1433
12345