Copper catalyzed oxidative ortho-C-H benzoxylation of 2-phenylpyridines with benzyl alcohols and benzyl amines as benzoxylation sources

被引：23
|
作者：
Khemnar, Ashok B. [1 ]
Bhanage, Bhalchandra M. [1 ]
机构：
[1] Inst Chem Technol, Dept Chem, Mumbai, Maharashtra, India
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2014年 / 12卷 / 47期
关键词：
N BOND FORMATION; ORTHO-ACETOXYLATION; 2-ARYLPYRIDINES; ACYLOXYLATION; SP(2); FUNCTIONALIZATION; ACTIVATION; OXYGENATION; AMIDATION;
D O I：
10.1039/c4ob01912a
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple and efficient protocol for the oxidative ortho benzoxylation of 2-phenylpyridines with benzyl alcohols and benzyl amines via C-H bond activation has been developed. The present protocol uses benzyl alcohol and benzyl amine as inexpensive and easily available starting materials to afford benzoxylation products in moderate to good yields in the presence of the Cu/TBHP catalytic system.
引用
收藏
页码：9631 / 9637
页数：7
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