Levulan®:: the first approved topical photosensitizer for the treatment of actinic keratosis

被引：51

作者：

Jeffes, EWB ^{[1
]}

机构：

[1] Vet Affairs Med Ctr, Div Dermatol, Long Beach, CA USA

来源：

JOURNAL OF DERMATOLOGICAL TREATMENT | 2002年 / 13卷 / 01期

关键词：

actinic keratosis; aminolevulinic acid; photodynamic therapy; squamous cell carcinoma;

D O I：

10.1080/095466302317414663

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Actinic keratosis (AK) is a very common skin problem found in patients over 50 years of age, representing an in situ keratinocytic neoplasm that can progress to invasive squamous cell carcinoma of the skin. One Food and Drug Administration-approved treatment for AK of the face and scalp is photodynamic therapy (PDT) with 20% aminolevulinic acid (ALA). This advanced technology has been demonstrated in clinical trials to be effective and well tolerated by patients.

引用

页码：S19 / S23

页数：5

共 8 条

[1] Actinic keratoses [J].

Callen, JP ;

Bickers, DR ;

Moy, RL .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1997, 36 (04) :650-653

[2] The treatment of actinic keratoses [J].

Dinehart, SM .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2000, 42 (01) :S25-S28

[3] Actinic keratosis: Current treatment options [J].

Jeffes III E.W.B. ;

Tang E.H. .

American Journal of Clinical Dermatology, 2000, 1 (3) :167-179

[4] Photodynamic therapy of actinic keratosis with topical 5-aminolevulinic acid - A pilot dose-ranging study [J].

Jeffes, EW ;

McCullough, JL ;

Weinstein, GD ;

Fergin, PE ;

Nelson, JS ;

Shull, TF ;

Simpson, KR ;

Bukaty, LM ;

Hoffman, WL ;

Fong, NL .

ARCHIVES OF DERMATOLOGY, 1997, 133 (06) :727-732

[5] Photodynamic therapy of actinic keratoses with topical aminolevulinic acid hydrochloride and fluorescent blue light [J].

Jeffes, EW ;

McCullough, JL ;

Weinstein, GD ;

Kaplan, R ;

Glazer, SD ;

Taylor, JR .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2001, 45 (01) :96-104

[6]

LING M, 2001, AM AC DERM 29 JUL 2

[7] Clinical presentation of actinic keratoses and squamous cell carcinoma [J].

Moy, RL .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2000, 42 (01) :S8-S10

[8] Topical aminolevulinic acid HCl photodynamic therapy [J].

Ormrod D. ;

Jarvis B. .

American Journal of Clinical Dermatology, 2000, 1 (2) :133-139

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