Effect of heparin on infection of cells by equine arteritis virus

被引：12
作者：
Asagoe, T
Inaba, Y
Jusa, ER
Kouno, M
Uwatoko, K
Fukunaga, Y
机构：
[1] NIHON UNIV,COLL BIORESOURCE SCI,DEPT VET EPIZOOTIOL,FUJISAWA,KANAGAWA 252,JAPAN
[2] NIHON UNIV,COLL BIORESOURCE SCI,DEPT VET VIROL,FUJISAWA,KANAGAWA 252,JAPAN
[3] JAPAN RACING ASSOC,EQUINE RES INST,EPIZOOT RES STN,KOKUBUNJI,TOCHIGI 32904,JAPAN
来源：
JOURNAL OF VETERINARY MEDICAL SCIENCE | 1997年 / 59卷 / 08期
关键词：
equine arteritis virus; heparin; inhibitory effect;
D O I：
10.1292/jvms.59.727
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
The number of plaques formed by equine arteritis virus (EAV) and Aujesky's disease virus (ADV) was reduced to 14% and 5% of the untreated control(100%), respectively, by 10 U/ml of heparin, but could not be reduced below to 13 and 4%, respectively, by use of concentration up to 100 U/ml. An inhibitory effect of heparin, at concentration up to i00 U/ml, was nor observed on parainfluenza virus 3 (PIV-3). Heparinase treatment of RK13 cells reduced the number of EAV-, as well as ADV-induced plaques. On the other hand, the number of PIV-3 induced plaques did not decrease after treatment of RK13 cells with heparinase.
引用
收藏
页码：727 / 728
页数：2
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