Effect of heparin on infection of cells by equine arteritis virus

被引：12

作者：

Asagoe, T

Inaba, Y

Jusa, ER

Kouno, M

Uwatoko, K

Fukunaga, Y

机构：

[1] NIHON UNIV,COLL BIORESOURCE SCI,DEPT VET EPIZOOTIOL,FUJISAWA,KANAGAWA 252,JAPAN

[2] NIHON UNIV,COLL BIORESOURCE SCI,DEPT VET VIROL,FUJISAWA,KANAGAWA 252,JAPAN

[3] JAPAN RACING ASSOC,EQUINE RES INST,EPIZOOT RES STN,KOKUBUNJI,TOCHIGI 32904,JAPAN

来源：

JOURNAL OF VETERINARY MEDICAL SCIENCE | 1997年 / 59卷 / 08期

关键词：

equine arteritis virus; heparin; inhibitory effect;

D O I：

10.1292/jvms.59.727

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The number of plaques formed by equine arteritis virus (EAV) and Aujesky's disease virus (ADV) was reduced to 14% and 5% of the untreated control(100%), respectively, by 10 U/ml of heparin, but could not be reduced below to 13 and 4%, respectively, by use of concentration up to 100 U/ml. An inhibitory effect of heparin, at concentration up to i00 U/ml, was nor observed on parainfluenza virus 3 (PIV-3). Heparinase treatment of RK13 cells reduced the number of EAV-, as well as ADV-induced plaques. On the other hand, the number of PIV-3 induced plaques did not decrease after treatment of RK13 cells with heparinase.

引用

页码：727 / 728

页数：2

共 10 条

[1]

DOLL E. R., 1957, CORNELL VET, V47, P3

[2]

INABA Y, 1963, JPN J EXP MED, V33, P313

[3]

Jusa ER, 1997, AM J VET RES, V58, P488

[4] INTERACTION OF GLYCOPROTEIN-GIII WITH A CELLULAR HEPARINLIKE SUBSTANCE MEDIATES ADSORPTION OF PSEUDORABIES VIRUS [J].