Epigenetic reprogramming in solid tumors: therapeutic implications of EZH2 gain-of-function mutations

被引：2

作者：

Barsotti, Anthony M. ^{[1
,2
]}

Ryskin, Michael ^{[1
]}

Rollins, Robert A. ^{[1
]}

机构：

[1] Pfizer Worldwide Res & Dev, Oncol Res Unit, Pearl River, NY 10965 USA

[2] Kadmon Pharmaceut, New York, NY 10016 USA

来源：

EPIGENOMICS | 2015年 / 7卷 / 05期

关键词：

epigenetic reprogramming; epigenetic therapy; EZH2; gain-of-function mutations; histone methylation; melanoma; polycomb; B-CELL LYMPHOMAS; LYSINE; 27; MELANOMA; CANCER; HYPERTRIMETHYLATION; INHIBITION; EXPRESSION; LANDSCAPE; PROTEINS; TARGET;

D O I：

10.2217/epi.15.27

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

[No abstract available]

引用

页码：687 / 690

页数：4

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