Epigenetic reprogramming in solid tumors: therapeutic implications of EZH2 gain-of-function mutations

被引：2
|
作者：
Barsotti, Anthony M. [1 ,2 ]
Ryskin, Michael [1 ]
Rollins, Robert A. [1 ]
机构：
[1] Pfizer Worldwide Res & Dev, Oncol Res Unit, Pearl River, NY 10965 USA
[2] Kadmon Pharmaceut, New York, NY 10016 USA
来源：
EPIGENOMICS | 2015年 / 7卷 / 05期
关键词：
epigenetic reprogramming; epigenetic therapy; EZH2; gain-of-function mutations; histone methylation; melanoma; polycomb; B-CELL LYMPHOMAS; LYSINE; 27; MELANOMA; CANCER; HYPERTRIMETHYLATION; INHIBITION; EXPRESSION; LANDSCAPE; PROTEINS; TARGET;
D O I：
10.2217/epi.15.27
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
[No abstract available]
引用
收藏
页码：687 / 690
页数：4
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