Fatal hemothorax caused by pleural mesothelioma in a lion

被引：0
作者：
Rocha, Paulo Ricardo D. [1 ,2 ]
Duarte, Roberta P. [2 ]
Laranjeira, Maria Gisela [2 ]
Melo, Tawane Agda L. [2 ]
Azevedo, Eustaquio Z. [3 ]
Garcia, Sergio D. [2 ]
Machado, Gisele F. [2 ]
机构：
[1] Univ Paulista Unip, Ctr Pesquisas, Ave Jose Maria Whitaker 290, BR-04057000 Sao Paulo, SP, Brazil
[2] Univ Estadual Paulista Julio de Mesquita Filho Un, Fac Med Vet, Rua Clovis Pestana 793, BR-16050680 Aracatuba, SP, Brazil
[3] Zool Municipal Aracatuba, Rua Fico S-N, BR-16050387 Aracatuba, SP, Brazil
来源：
PESQUISA VETERINARIA BRASILEIRA | 2019年 / 39卷 / 06期
关键词：
Hemothorax; pleural mesothelioma; immunohistochemistry; Panthera leo; lion; mesothelioma; zoo animal; wildlife animals; pathology;
D O I：
10.1590/1678-5150-PVB-6184
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Mesothelioma is considered a malignant neoplasm caused by the proliferation of mesothelial cells mostly from the pleura, peritoneum and pericardium. Here we described a case of fatal hemothorax caused by pleural mesothelioma in a lion by means of necropsy, histopathology and immunohistochemistry. Gross inspection of the thoracic cavity showed hemothorax with about 4 liters of blood. Microscopically, numerous, randomly distributed, soft, red-pink, irregular masses with up to 1cm in diameter were observed in both visceral and parietal pleurae. Microscopically, a papillary structure pattern was observed in the thoracic masses, composed mainly by one layer of cubic mesothelial cells, which presented eosinophilic cytoplasm, central nucleus and evident nucleolus, supported by a low cellular fibrovascularstroma. Neoplastic cells were positive for both cytokeratin and vimentin by immunohistochemistry. This seems to be the first report of fatal hemothorax caused by pleural mesothelioma in a lion.
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收藏
页码：416 / 418
页数：3
相关论文
共 12 条
  • [1] Malignant pleural mesothelioma in a female Lion (Panthera leo)
    Bollo, E.
    Scaglione, F. E.
    Tursi, M.
    Schroeder, C.
    Degiorgi, G.
    Belluso, E.
    Capella, S.
    Bellis, D.
    [J]. RESEARCH IN VETERINARY SCIENCE, 2011, 91 (01) : 116 - 118
  • [2] Brown CC, 2007, Jubb, Kennedy and Palmer's pathology of domestic animals, V2, P1
  • [3] Caswell J.L., 2007, PATHOLOGY DOMESTIC A, V2, P523
  • [4] Pleural malignant mesothelioma in a captive clouded leopard (Neofelis nebulosa nebulosa)
    Cunningham, AA
    Dhillon, AP
    [J]. VETERINARY RECORD, 1998, 143 (01) : 22 - 24
  • [5] Mesothelioma and asbestos
    Gibbs, Graham W.
    Berry, Geoffrey
    [J]. REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2008, 52 (01) : S223 - S231
  • [6] Head K. W., 2002, Tumors in domestic animals, P401, DOI 10.1002/9780470376928.ch8
  • [7] Abdominal mesothelioma in a goat
    Krametter, R
    Bagó, Z
    Floeck, M
    Baumgartner, W
    [J]. NEW ZEALAND VETERINARY JOURNAL, 2004, 52 (05) : 293 - 296
  • [8] SPONTANEOUS HEMOTHORAX - REPORT OF 6 CASES AND REVIEW OF THE LITERATURE
    MARTINEZ, FJ
    VILLANUEVA, AG
    PICKERING, R
    BECKER, FS
    SMITH, DR
    [J]. MEDICINE, 1992, 71 (06) : 354 - 368
  • [9] Non-coagulopathic spontaneous hemothorax in dogs
    Nakamura, Reid K.
    Rozanski, Elizabeth A.
    Rush, John E.
    [J]. JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 2008, 18 (03) : 292 - 297
  • [10] Snaebjornsson Petur, 2011, Patholog Res Int, V2011, P836054, DOI 10.4061/2011/836054
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