Synthesis of cyclic poly(l-lactide) catalyzed by Bismuth Salicylates-A combination of two drugs

被引：16

作者：

Kricheldorf, Hans R. ^{[1
]}

Weidner, Steffen M. ^{[2
]}

Scheliga, Felix ^{[1
]}

机构：

[1] Inst Tech & Makromol Chem, Bundesstr 45, D-20146 Hamburg, Germany

[2] BAM, Fed Inst Mat Res & Testing, Richard Willstatter Str 11, D-12489 Berlin, Germany

来源：

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY | 2019年 / 57卷 / 19期

关键词：

bismuth; cyclization; Polylactide; salicylic acid; toxicity; ring-opening polymerization; RING-OPENING POLYMERIZATION; L-LACTIDE; EXPANSION POLYMERIZATION; ACID; POLYLACTONES; MECHANISM; CRYSTALLIZATION; COPOLYMERS; TRIBLOCK; KINETICS;

D O I：

10.1002/pola.29473

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

l-lactide was polymerized in bulk at 160 or 180 degrees C with mixtures of bismuth subsalicylate (BiSub) and salicylic (SA) as catalysts. The SA/Bi ratio and the monomer/Bi ratio were varied. The highest molecular weights (weight average, Mw) were achieved at a SA/Bi ratio of 1/1 (Mw up to 92 000 g mol(-1)). l-Lactide was also polymerized with combinations of BiSub and silylated SA, and Mw values up to 120 000 g mol(-1) were achieved at 180 degrees C. MALDI-TOF mass spectrometry and Mark-Houwink-Sakurada measurements proved that under optimized reaction conditions the resulting polylactides consist of cycles. (c) 2019 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2019

引用

页码：2056 / 2063

页数：8

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