A possible role of collagen fibrils in the process of calcification observed in the capsule of the pineal gland in aging rats

被引：8
|
作者：
Humbert, W [1 ]
Cuisinier, F [1 ]
Voegel, JC [1 ]
Pevet, P [1 ]
机构：
[1] INSERM,FEDERAT RECH ODONTOL,U424,F-67085 STRASBOURG,FRANCE
来源：
CELL AND TISSUE RESEARCH | 1997年 / 288卷 / 03期
关键词：
calcification; concretions; collagen; pineal gland; aging; rat (Wistar);
D O I：
10.1007/s004410050830
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The relationship between collagen fibrils and calcified concretions exclusively appearing in the pineal gland of adult/aging rats has been investigated. Deposits of lanthanum, which replace calcium ions are distributed along collagen fibrils with a repeating period of about 70 nm, Calcium has been detected histochemically between collagen bundles surrounding extracellular concretions by means of the pyroantimonate method and by X-ray microanalysis. It is associated with phosphorus. The data presented here suggest that collagen fibrils are involved in the genesis and growth of extracellular concretions located in the connective tissue surrounding the pineal gland of aging rats.
引用
收藏
页码：435 / 439
页数：5
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