Cardiovascular Disease Risk Score: Results from the Filipino-American Women Cardiovascular Study

Introduction Although cardiovascular disease (CVD) is a leading cause of morbidity and mortality of Filipino-Americans, conventional CVD risk calculators may not be accurate for this population. CVD risk scores of a group of FilipinoAmerican women (FAW) were measured using the major risk calculators. Secondly, the sensitivity of the various calculators to obesity was determined. Methods This is a cross-sectional descriptive study that enrolled 40-65-year-old FAW (n = 236), during a community-based health screening study. Ten-year CVD risk was calculated using the Framingham Risk Score (FRS), Reynolds Risk Score (RRS), and Atherosclerotic Cardiovascular Disease (ASCVD) calculators. The 30year risk FRS and the lifetime ASCVD calculators were also determined. Results Levels of predicted CVD risk varied as a function of the calculator. The 10-year ASCVD calculator classified 12% of participants with >= 10% risk, but the 10-year FRS and RRS calculators classified all participants with <= 10 % risk. The 30year "Hard" Lipid and BMI FRS calculators classified 32 and 43 % of participants with high (>= 20 %) risk, respectively, while 95 % of participants were classified with >= 20 % risk by the lifetime ASCVD calculator. The percent of participants with elevated CVD risk increased as a function of waist circumference for most risk score calculators. Conclusions Differences in risk score as a function of the risk score calculator indicate the need for outcome studies in this population. Increased waist circumference was associated with increased CVD risk scores underscoring the need for obesity control as a primary prevention of CVD in FAW.