Facile aromatisation of Hantzsch 1,4-dihydropyridines by autoxidation in the presence of p-toluenesulfonic acid in acetic acid

被引：3

作者：

Zhang, Ding ^{[1
]}

Sha, Min ^{[2
]}

机构：

[1] Nanjing Univ Sci & Technol, Sch Chem Engn, Nanjing 210094, Jiangsu, Peoples R China

[2] Nanjing Univ Finance & Econ, Sch Management Sci & Engn, Nanjing 210046, Jiangsu, Peoples R China

来源：

JOURNAL OF CHEMICAL RESEARCH | 2018年 / 03期

基金：

中国国家自然科学基金;

关键词：

autoxidation; dehydrogenation; free radicals; heterocycles; catalysis; OXIDATIVE AROMATIZATION; 1,3,5-TRISUBSTITUTED PYRAZOLINES; MOLECULAR-OXYGEN; EFFICIENT; CATALYST; CARBON; MODEL;

D O I：

10.3184/174751918X15208600846791

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple protocol to achieve the aromatisation of Hantzsch dihydropyridines in high yield was established using p-toluenesulfonic acid in acetic acid and yields of 90% were obtained at room temperature. With regards to the Hantzsch 1,4-dihydropyridines derived from alkyl aldehydes bearing one or more a-hydrogens, dealkylation products were obtained through a proposed autoxidation mechanism.

引用

页码：141 / 144

页数：4

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