Effects of evolving lipid-lowering drugs on carbohydrate metabolism

被引:2
|
作者
Tsimihodimos, V. [1 ]
Elisaf, M. [1 ]
机构
[1] Univ Ioannina, Sch Med, Dept Internal Med, Niarchou Ave, GR-45110 Ioannina, Greece
关键词
Antisense oligonucleotides; PCSK9; inhibitors; Apolipoprotein CIII inhibitors; CETP inhibitors; Lp(a); LOW-DENSITY-LIPOPROTEIN; OF-FUNCTION MUTATIONS; ALPHA/DELTA AGONIST GFT505; APOLIPOPROTEIN C-III; TARGETING APOLIPOPROTEIN(A); GLUCOSE-HOMEOSTASIS; INSULIN SENSITIVITY; DOUBLE-BLIND; BETA-CELLS; HIGH-RISK;
D O I
10.1016/j.diabres.2017.12.012
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The understanding that statins reduce but not eliminate the cardiovascular risk associated with disturbed lipid metabolism and the existence of forms of dyslipidemia that are unresponsive or only partially responsive to statins have led to the development of many novel lipid-lowering drugs. Accumulating evidence suggests that the interplay between carbohydrate and lipid metabolism is bidirectional. Thus, any intervention that affects lipid metabolism has the potential to influence the homeostasis of glucose. In this review we summarize the available data on the effects of the evolving lipid-lowering drugs on carbohydrate metabolism. (C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码:1 / 9
页数:9
相关论文
共 50 条
  • [1] PSYCHOLOGICAL EFFECTS OF LIPID-LOWERING DRUGS
    HOUSTON, BK
    DUJOVNE, CA
    BABYAK, MA
    PSYCHOSOMATIC MEDICINE, 1994, 56 (02): : 165 - 165
  • [2] Effects of Lipid-Lowering Drugs on Adiponectin
    Perelas, Apostolos
    Tsoulkani, Anna
    Perrea, Despina
    CURRENT VASCULAR PHARMACOLOGY, 2010, 8 (06) : 836 - 848
  • [3] The role of cellular lipid metabolism and lipid-lowering drugs in periodontitis
    Kiarashi, Mohammad
    Yasamineh, Saman
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2025, 152
  • [4] Lipid-Lowering Drugs
    不详
    MEDICAL LETTER ON DRUGS AND THERAPEUTICS, 2016, 58 (1506): : 133 - 140
  • [5] Lipid-Lowering Drugs
    不详
    MEDICAL LETTER ON DRUGS AND THERAPEUTICS, 2022, 64 (1659): : 145 - +
  • [6] Lipid-lowering drugs
    K. Pahan
    Cellular and Molecular Life Sciences CMLS, 2006, 63 : 1165 - 1178
  • [7] LIPID-LOWERING DRUGS
    不详
    MEDICAL LETTER ON DRUGS AND THERAPEUTICS, 1980, 22 (16): : 65 - 66
  • [8] LIPID-LOWERING DRUGS
    THOMPSON, GR
    LANCET, 1988, 1 (8585): : 597 - 597
  • [9] Lipid-Lowering Drugs
    不详
    MEDICAL LETTER ON DRUGS AND THERAPEUTICS, 2019, 61 (1565): : 17 - 24
  • [10] Lipid-lowering drugs
    Andréjak, M
    Caron, J
    Libersa, C
    Thery, C
    THERAPIE, 2003, 58 (01): : 1 - 2