Assessment of visual fixation in vegetative and minimally conscious states

被引：27
作者：
Di, Haibo [1 ,2 ]
Nie, Yunzhi [1 ]
Hu, Xiaohua [1 ,3 ]
Tong, Yong [1 ,4 ]
Heine, Lizette [2 ]
Wannez, Sarah
Huang, Wangshan [1 ]
Yu, Dan [1 ,3 ]
He, Minhui [1 ]
Thibaut, Aurore [2 ]
Schnakers, Caroline [2 ]
Laureys, Steven [2 ]
机构：
[1] Hangzhou Normal Univ, Internat Vegetat State & Consciousness Sci Inst, Hangzhou 310036, Peoples R China
[2] Univ & Univ Hosp Liege, Cyclotron Res Ctr, Dept Neurol, Coma Sci Grp, Liege, Belgium
[3] Wujing Hosp Hangzhou, Hangzhou, Peoples R China
[4] Huzhou Ctr Hosp, Huzhou, Peoples R China
来源：
BMC NEUROLOGY | 2014年 / 14卷
基金：
中国国家自然科学基金;
关键词：
Disorders of consciousness; Vegetative state; Unresponsive wakefulness syndrome; Minimally conscious state; Visual fixation; POST-COMATOSE STATES; DISORDERS; BEHAVIOR;
D O I：
10.1186/1471-2377-14-147
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Background: Visual fixation plays a key role in the differentiation between vegetative state/unresponsive wakefulness (VS/UWS) syndrome and minimally conscious state (MCS). However, the use of different stimuli changes the frequency of visual fixation occured in patients, thereby possibly affecting the accuracy of the diagnosis. In order to establish a standardized assessment of visual fixation in patients in disorders of consciousness (DOC), we compared the frequency of visual fixation elicited by mirror, a ball and a light. Method: Visual fixation was assessed in eighty-one post-comatose patients diagnosed with a MCS or VS/UWS. Occurrence of fixation to different stimuli was analysis used Chi-square testing. Result: 40 (49%) out of the 81 patients showed fixation to visual stimuli. Among those, significantly more patients (39, 48%) had visual fixation elicited by mirror compared to a ball (23, 28%) and mirror compared to a light (20, 25%). Conclusion: The use of a mirror during the assessment of visual fixation showed higher positive response rate, compared to other stimuli in eliciting a visual fixating response. Therefore, fixation elicited by a mirror can be a very sensitive and accurate test to differentiate the two disorders of consciousness.
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页数：6
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