Lowering intra-ocular pressure is always a necessity to treat glaucoma. Others identified risks factors may be fought, with the hope to favourably act on the disease: arteriosclerosis worsening parameters, tow diastolic arterial pressure, vasospastic or steep apnea syndrome, inverse pupillary block in pigmentary dispersion. On the other hand, ignoring a noctural closure of the irido-corneal angle or a non-compliance to the medical treatment may lead to glaucoma worsening. (C) 2009 Elsevier Masson SAS. All rights reserved.